formative questions - learn well Flashcards

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1
Q

are mucosal membranes highly specialised for function?

A

yes

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2
Q

what is a strain of MRSA which causes NF?

A

PVL

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3
Q

impetigo like mark around the mouth are described as being a …

A

vesicle

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4
Q

is a macule raised or flat?

A

flat

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5
Q

what is a macule described as

A

an area of skin discolouration

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6
Q

when do sweat glands develop

A

6 months gestation

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7
Q

which cells migrate from the skin to the neural crest

A

melanocytes

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8
Q

which layer is most metabolically active

A

basal

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9
Q

which percentage of GP consultations are derm realted

A

19%

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10
Q

boy with type 1 skin - skin but red in sun, crying and rubbing skin

A

erythropoietic protoporphyria

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11
Q

definition of impeding

A

enables organism to avoid host defence mechanism

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12
Q

definition on modulin

A

causes damage to host indirectly

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13
Q

definition of aggressin

A

causes damage to host directly

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14
Q

which cells carry out vit d metabolism

A

keratinocytes

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15
Q

which part is responsible for energy strorage

A

subcutaneous fat

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16
Q

which component is responsible for tensile strength

A

collagen

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17
Q

which cells are responsible for epidermal proliferation

A

basal cells

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18
Q

when does erythropoietic protoporphyria present

A

early childhood

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19
Q

what are the symptoms of EP

A

discomfort
itch
tingling in sun exposed skin
no clinical signs

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20
Q

what is the deficiency of EP And what does it cause build up of

A

ferrochelastase

protoporphyrin IX

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21
Q

what is the lunula

A

white crescent moon part of nail

its the visible part of the root of the nail

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22
Q

what is the hyponychium

A

the bit underlying the free part of the nail

23
Q

where are langerhan cells formed

A

bone marrow

24
Q

deficiency in AIP and what does it result in

A

porphobilinogen deaminase

results in acute neurotoxic reaction in many tissues

25
Q

what are the commonest sweat glands on the face

A

eccrine glands

26
Q

which glands control temperature regulation

A

eccrine glands

27
Q

which glands are involved in sent

A

apocrine glands

28
Q

where are keratinocytes confined to

A

the epidermis

29
Q

are topical steroids lipophilic or phobic and what does this allow?

A

lipophilic - this allows passive diffusion across the plasma membrane where they combine with cell receptors and bind to steroid responsive elements in the DNA

30
Q

which layer has big dips in it

A

prickle cell layer

31
Q

which layer has odland bodies

A

granular layer

32
Q

which layer has polyhedral cells with lots of desmosomes

A

prickle cell layer

33
Q

hair growing on cheeks?

A

PCT

34
Q

how many days does it take for cells to migrate from the basal layer to keratin layer

A

28 days

35
Q

when are nuclei lost

A

starts in granular layer and completed in keratin layer

36
Q

what percent of the keratin layer is made from keratin and fillagrin

A

80%

37
Q

how many cells thick is the granular layer

A

2-3

38
Q

definition of lichenification

A

when the skin becomes thick and rubbery as a result of scratching

39
Q

tinea cruris

A

groin

40
Q

tinea unguium

A

nails

41
Q

definition of cream

A

semisolid emulsion of oil in water, containing preservative

42
Q

definition of gel

A

thickened aqueous solution

43
Q

tuberose sclerosis inheritance pattern

A

autosomal dominant

44
Q

rosacea relationship to sebaceous glands?

A

hyperplasia but sebum excretion is normal

45
Q

who does rosace affect

A

commoner in women but more severe in men

46
Q

HPV warts/verucas types

A

1-4

47
Q

HPV types for genital warts

A

6 +11

48
Q

HPV for cervical cancer

A

16 + 18

49
Q

why are creams more likely to cause an allergic reaction than ointments?

A

they contain preservatives

50
Q

where are arterial ulcers seen

A

occur on the foot or the mid shin

51
Q

where are pressure ulcers seen

A

affect the area of skin in contact with the source of pressure e.g. a bed = sacrum, heels, ischaea, greater trochanters

52
Q

where are venous ulcers seen

A

lateral or medial malleolus

53
Q

what is the definition of anchoring

A

the tendency to perceptually lock onto salient features in the patients initial presentation too early int he diagnostic process, and failing to adjust this initial impression in the light of later information

54
Q

what is the definition of avaliability

A

the disposition to judge things as becoming more likely or frequently occurring, if they readily come to mind