Treatments 2 Flashcards
Burns
1st/minor 2nd degree - outpatient, antimicrobial agents (topical silver sulfadiazine or bacitracin)
2nd >10%, 3rd >2%, 2nd/3rd on hands, face, genitalia, major flexion areas - inpatient
2nd/3rd >25% or face - airway management
Drowning
Airway, supplemental O2, NG tube, maintain temp, admission for any symptoms of hypoxia
Choking
Active coughing
Heimlich if unable to breathe
Emergency tracheotomy if continued obstruction
Bronchoscopy for visualization and removal (IV corticosteroids first may decrease inflammation)
Heat exhaustion
Hyrdation, electrolyte replacement
Heat stroke
Cool patient, benzos if seizures
Hypothermia
Warm patient, treat arrhythmias/hypotension as needed
Snake bite
Immobilize extremity
Clean wound
Antivenin
Scorpion bite
Antivenin
Atropine / phenobarbital for symptoms
Black widow bite
Local wound care
Antivenin
24 hr observation for systemic symptoms
Benzos if symptoms
Brown recluse bite
Local wound care
Dapsone to prevent necrosis
Oral erythromycin if infx
Dog/cat bite
Irrigation
Tetanus and rabies prophylaxis
Antibiotics if infx
Leave open on arm/hand, cat bite; close on face
Human bite
Irrigation
Antibiotics (amoxicillin-clavulanate)
PUD
+H pylori: amoxicillin + clarithromycin + PPI
-H pylori: PPI/H2 blocker
BPH
Alpha 1 blockers (doxazosin, tamsulosin)
5-alpha reductase inhibitors (finasteride)
Possible surgery
Atherosclerosis
Prevention Stop smoking Control HTN Control hyperglycemia Control hypercholesteremia (statins, also have anti-inflammatory properties and stabilize plaques) Diet low in fat and cholesterol
Lower LDL
Statins (best)
Ezetimibe
Bile acid resins
(Fibrates)
Lower TG
Fibrates
Omega 3 FA
Statins (minor)
Raise HDL
Niacin
Statins (minor)
Stable angina
Sublingual nitro (peripheral venous vasodilator, reduces preload, reduces myocardial O2 demand) Also helps esophageal pain (GERD, spasm)
Prinzmetal angina (arterial vasospasm)
CCB (either type)
also nitrates
Unstable angina, acute
ABCs MONA (O2 only in hypoxemic patients) BB (if no heart failure; careful in COPD, asthma, DM) Statin (preferably before PCI) Antiplatelet therapy Anticoagulant therapy K>4, Mg>2
Unstable angina, home
BB, ASA, nitroglycerin, statin, antiplatelet (1-12 months), ACE/ARB (DM, CHF, HTN)
Unstable angina, nonresponsive to medications
PTCA (balloon catheter w/ or w/o stent)
NO fibrinolysis
Indications for CABG
Left main stenosis >50%
Three vessel disease
Hx CAD and DM
MI, acute
MONA Anticoagulant (heparin/LMWH) BB Statin Antiplatelet K>4, Mg>2 PCI if possible (use LMWH, add Gp IIb/IIIa inhibitor to AP) If no PCI available w/i 12 hrs, consider fibrinolysis w/ tPA (must be w/i 12 hrs, sooner is better) Cath to see if PTCA/CABG needed
MI, home
ASA or clopidogrel BB* ACE* Aldosterone antagonist Statin* *Improve mortality
Dressler syndrome
NSAIDs or ASA
1st degree heart block
None
2nd degree heart block, Mobitz type I (Wenckebach)
Adjust medication dose
None
Symptomatic bradycardia, maybe pacemaker
2nd degree heart block, Mobitz type II
Pacemaker (can progress to 3rd degree)
3rd degree heart block
Pacemaker
PSVT, AV nodal reentry
Carotid massage, Valsalva maneuver
DOC: IV adenosine (6 mg, 12 mg, 12 mg)
Cardioversion or CCB for hemodynamic instability
BB or CCB for long-term symptomatic patients
PSVT, Wolff-Parkinson-White syndrome
Carotid massage, Valsalva maneuver
DOC: IV adenosine (6 mg, 12 mg, 12 mg)
Cardioversion or CCB for hemodynamic instability
1A or 1C antiarrhythmic or catheter ablation for long-term symptomatic patients
MAT
CCB (NDP, verapamil/diltiazem) or BB
K >4, Mg >2
Catheter ablation or surgery if needed
Bradycardia
Stop precipitating medication
IV atropine
Pacemaker if severe
AFib
Anticoagulation
Rate control (BB/CCB, digoxin) or rhythm control (Class III)
Synched cardioversion if <48 hrs
Look for thrombus with TEE
If over 2 days or thrombus seen, anticoagulate and wait 3-4 wks before cardioversion
AV nodal ablation for recurrence
AFlutter
Rate control (BB/CCB)
Electrical or chemical cardioversion if canβt control w/ medication
Catheter ablation may be possible
Chemical cardioversion
Class IA, IC, III antiarrhythmics
PVC
None if healthy
BB if patient w/ CAD
VTach (w/ pulse)
Rapid infusion amiodarone (first line)
Or procainamide/sotalol
Synched cardioversion if no drugs available
Internal defibrillator may be needed for recurrent
Torsades de pointes
Magnesium (large rapid IV bolus)
VFib, VTach (pulseless)
CPR, immediate electrical cardioversion (360J) Q2 min
Epinephrine 1 mg Q3-5 min [NO max dose]
Vasopressin 40 un in place of 1st/2nd dose epi
Consider amiodarone 300 mg IV then 150 mg IV
Consider Lidocaine 1-1.5 mg/kg up to 3 mg/kg total
Unresponsive patient w/ pulse
Resuce breathing (1 breath Q5-6 sec)
Unresponsive patient w/o pulse
CPR 30:2
Check rhythm
PEA/Asystole
CPR 30:2
Epinephrine 1 mg Q3-5 min [NO max dose]
Vasopressin 40 un in place of 1st/2nd dose epi
Evaluate and treat causes (H&Ts)
PEA/Asystole caused by Hypovolemia
Rapid volume resuscitation through multiple IVs or central line
PEA/Asystole caused by Hypoxia
Intubation, chest tube or oxygen
PEA/Asystole caused by H ions (acidosis)
IV push 1-2 amps bicarb
Common in prolonged code
PEA/Asystole caused by Hyperkalemia
CaCl2 IV push
Bicarb, Insulin/glucose to push K into cells
(Common in prolonged code from acidosis)
PEA/Asystole caused by Hypokalemia
KCl
PEA/Asystole caused by Hypoglycemia
(Always check finger stick)
1 amp D50 IV push
PEA/Asystole caused by Hypothermia
Warming
PEA/Asystole caused by Tamponade
Pericardiocentesis
PEA/Asystole caused by Tension pneumothorax
Needle decompression then chest tube
PEA/Asystole caused by Thrombosis (MI)
Cardiac cath or thrombolytic
PEA/Asystole caused by Thrombosis (PE)
Thrombolytic or thrombectomy
PEA/Asystole caused by Trauma
Follow ATLS protocols (ABC, etc)
CHF, acute exacerbation
NO LIP Nitrates (dilate veins>arteries, work faster than diuretics) Oxygen (if hypoxemic) Loop diuretics Inotropes (last resort) Positioning (feet down to clear lungs)
CHF, chronic outpatient (mortality vs symptoms)
Improves mortality - ACE, some ARB - BB (bisoprolol, carvedilol, ER metoprolol) - Spironolactone/eplerenone Symptoms - Loop diuretic - Digoxin - VD if also needed (isosorbide dinitrate reduces preload, hydralazine reduces afterload)
Progressive chronic CHF
May need biventricular pacing or cardiac resynch therapy (pacemaker at EF <35% for 3 months)
May need cardiac transplant
Acute pericarditis
Treat underlying cause
NSAIDs for pain, inflammation
Pericardiocentesis for large effusions
Chronic constrictive pericarditis
NSAIDs, colchicine, corticosteroids
Surgical excision of pericardium (high mortality)
Cardiac tamponade
(Dx w/ echo)
Immediate pericardiocentesis
Hypertrophic cardiomyopathy
BETA BLOCKERS
CCB, pacemaker, partial septal excision
Dilated cardiomyopathy
Treat like heart failure
Diuretics, ACE, BB, AC
Restrictive cardiomyopathy
Treat underlying cause
Palliative treatment for heart failure
Myocarditis
Treat infection / stop offending medications
Avoid exertional activity
Treat heart failure symptoms
Acute rheumatic fever
NSAIDs for joint inflammation
Corticosteroids if severe carditis
B-lactam if GAS infection still present
Endocarditis
Long term IV antibiotics (4-6 wks) (B-lactam plus aminoglycoside like ceftriaxone + gentamicin, maybe also vancomycin for MRSA)
Antibiotic prophylaxis before surgery or dental work
Valve replacement if severe valve damage
Antibiotic prophylaxis for endocarditis
2 gm amoxicillin 30-60 min before procedure (nothing after)
HTN emergency
Rapidly reduce diastolic BP to 100 mmHg (use IV anti-HTN, also start oral BB/ACE)
- Should not drop more than 25% in first 2 hrs (to avoid triggering ischemic event)
DIuretics to reduce pulmonary edema if needed
HTN, initial
Lifestyle (weightloss, exercise, salt restriction, alcohol reduction)
Thiazide diuretic unless comborbid C/I
HTN secondary to renal disease
ACEi (delays progression)
- C/I if acute renal failure (can accelerate)
- C/I if bilateral renal stenosis
- C/I if hyperkalemia (can worsen)
Renal artery stenosis
Angioplasty, stent placement, surgical repair
ACEi if one sided
Aortic coarctation
Surgical repair
HTN + DM
C/I
ACE
(+/- Thiazide diuretic, impaired glucose tolerance)
(+/- BB, can mask hypoglycemia symptoms)
HTN + CHF
C/I
ACE/ARB Aldosterone antagonist BB (NDP CCB, can exacerbate by reducing rate/contractility) (BB during acute exacerbation)
HTN + Post-MI
BB
ACE/ARB
Aldosterone antagonist
HTN + BPH
alpha-1-blocker (-zosins)
HTN + migraines
BB (or verapamil)
HTN + osteoporosis
Thiazide diuretic
HTN + Asthma/COPD (C/I)
Non-selective BB
HTN + Pregnancy
Hydralazine Methyldopa Labetalol Nifedipine (+/- Thiazide, esp starting; mild hypovolemia at start) (ACE/ARB, teratogenic)
HTN + Gout (C/I)
(Diuretic, increase serum uric acid)
HTN + Depression (C/I)
(BB, can worsen symptoms)
HTN + LVH
ACE/ARB
HTN + Hyperthyroidism
Propranolol
HTN + benign essential tremor
BB
HTN + post-menopausal woman
Thiazide (increase calcium)
HTN + Prinzmetal angina
DHP CCB
HTN + AFib or SVT
NDP CCB
HTN + esophageal spasm
DHP CCB
Nonhemolytic febrile transfusion rxn
Acetaminiophen
Acute hemolytic transfusion rxn
Aggressive supportive care
Delayed hemolytic transfusion rxn
No acute therapy needed; determine responsible Ab type to prevent future rxns
Anaphylactic transfusion rxn
Epinephrine, volume maintenance, airway protection; use extra washed blood products next time
Minor allergic transfusion rxn
Diphenhydramine
Post-transfusion purpura
IVIG or plasmapheresis
DOC in septic shock
NE
DOC in anaphylactic shock
Epinephrine
DOC in cardiogenic shock
Dobutamine
AAA
Monitor w/ US q6 months if 0.5 cm in 6 months or symptomatic
Aortic dissection
BB (nitroprusside second choice) to stabilize BP
Stanford A - emergency surgery
Stanford B - medical management
PVD/PAD
Smoking cessation, glucose/BP control
Daily exercise to increase collateral flow
Cilostazol (arterial VD) or pentoxifylline (+RBC flexibility)
ASA/clopidogrel; Statin
[cardiac stress test prior to surgery]
PTA for failed medical management, significant disability from claudication
Bypass grafting if incapacitating claudication, resting foot pain, necrotic foot lesions
Limb amputation for prolonged ischemia
Varicose veins
Weight reduction, leg elevation Compression stockings Sclerotherapy Thermal ablation Surgery w/ venous ligation
AVM
Surgical removal or sclerosis if symptomatic or located in brain or bowel
DVT
Leg elevation
Heparin then warfarin
IVC if c/i to AC
Polyarteritis nodosa
Corticosteroids, immunosuppressants
Temporal (giant cell) arteritis
High dose prednisone 1-2 months then taper
Low dose ASA
Vitamin D, calcium supplementation
Takayasu arteritis
Corticosteroids, immunosuppressants
Bypass grafting if needed
Allergic granulomatosis w/ angiitis (Churg-Strauss)
Corticosteroids, immunosuppressants
Henoch-Schonlein purpura
Usu self-limiting
Corticosteroids for severe symptoms
Kawasaki disease
IVIG (ideally w/i first 10 days)
High dose ASA until 48 hrs after fever resolution
Low dose ASA until inflammatory markers (ESR, platelets) return to normal (about 6 wks)
Echo in acute phase and 6-8 wks later
NO steroids
Thromboangiitis obliterans (Buerger disease)
Smoking cessation
Tetralogy of Fallot
PGE, O2, propranolol, IVF
Morphine, Tet position during cyanotic episodes
Surgical correction
Endocardial cushion defect
Surgical correction
Persistent truncus arteriosus
Surgical correction
Transposition of the great vessels
PGE
Balloon atrial septostomy to widen ASD/VSD
Prompt surgical correction
Patent ductus arteriosus
Indomethacin (after a week or two)
Surgical closure if unresponsive
Atrial septal defect
Small - observation
Symptomatic/large - surgical closure
Ventricular septal defect
Small - observation
Large - diuretics, ACEi, surgical repair
Ebstein anomaly
PGE, digoxin, diuresis, propranolol