Treatment Planning and Treatment Delivery (case studies) Flashcards

1
Q

what are features that are important in a TPS

A
  • Dose accuracy
  • Geometric accuracy
  • Dose to medium vs dose to water (e.g low density lung or high density bone?)
  • CT orientation cube
  • Moves from CTRP
  • Connectivity to CT
  • Connectivity to R&V system
  • Integrity of Plan transfer- MU, field size, MLC position, Control point, dose rate
  • Integrity of reference data (DRR or reference CT)
  • Plan Evaluation tools (DVH, Score cards)
  • Limitations in plan (e.g. spinal fields)
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2
Q

MU calculation for 3DCRT benefits and limitations

A

Benefit
* No measurement required
* Can predict dose to a point at various SSD, depth, field size, wedge, tray,
compensator, energy using reference data
* Independent MU/dose calculation

Limitation
* Flat geometry
* “radiological depth” does not accurately account for heterogeneity
* Heavily shielded fields
* Highly elongated field
* IMRT, VMAT, DCAT

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3
Q

factors to consider when choosing a device

A
  • Absolute vs Relative Dose
  • Treatment technique (IMRT, VMAT, FFF) – dose rate?
  • Resolution
  • Gamma Pass Criteria
  • Cost – Upfront and Ongoing
  • Compatibility with existing equipment (TPS, Linacs etc)
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4
Q

Common Causes for QA Failure

A

Plan-Evaluate your plan for potential for plan failure when you see:
* Lower MU Efficiency
* Modulation Factor (MU/cGy)
* Plan Complexity

Detector Limitation
* Elongated fields
* Detector non-uniformity
* Field size limitations

Treatment Equipment failure
* MLC failure
* Beam Symmetry
* Alignment of Optical system to radiation isocentre

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5
Q

High Complexity Fields

A
  • High MU per Gy ~typically a factor of 3 is produces a good plan
  • Narrow MLC aperture
  • Higher uncertainty during delivery
  • Apertures smaller than minimum calibrated field for EPIQA
  • Plan Complexity Metrics
  • Small aperture score
  • Modulation Factor
  • Modulation Complexity Score
  • Area/Perimeter
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6
Q

daily QA: Planar kV/MV/CBCT imaging

what it checks and the tolerances

A

collision interlocks –> functional

positioning –> non SBRT <2mm, SBRT <1mm

treatment and imaging isocentre coincidence –> non SBRT <2mm, SBRT <1mm

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7
Q

daily QA: dosimetry

what it checks and the tolerances

A

x-ray and electron output constancy –> non SBRT 3%, SBRT 3%

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8
Q

daily QA: mechanical

what it checks and the tolerances

A

laser localisation –> non SBRT 2mm, SBRT 1mm

optical distance indicator accuracy at isocentre –> non SBRT 2mm, SBRT 2mm

light field size –> non SBRT 2mm, SBRT 1mm

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9
Q

daily QA: safety

what it checks and the tolerances

A

door interlock, audio visual, beam on indicator

function or not functional

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10
Q

collision interlocks

reasons for failure and what happens if it doesn’t get fixed

A
  • Sensors failure
  • Electronics board failure
  • Gantry/Panel collision into patient causing injury
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11
Q

imaging Positioning and isocentre coincidence (kV, MV, CBCT)

reasons for failure and what happens if it doesn’t get fixed

A
  • Calibration file may have been
    corrupted/deleted/changed/recalibrated
  • Electronics may be incorrect/damaged
  • Incorrect source/detector positioning
  • Geometric misalignment for treatment
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12
Q

Wedge Morning Check out run one angle

reasons for failure and what happens if it doesn’t get fixed

A
  • EDW STT table may have been corrupted
  • All wedge fields would potentially be incorrectly treated
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13
Q

X-ray & Electron output constancy

reasons for failure and what happens if it doesn’t get fixed

A
  • Electronic drift of detector
  • Damage/Changes to the MU chamber require replacement or recalibration
  • incorrect dose delivered to all patients
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14
Q

Laser Localisation

reasons for failure and what happens if it doesn’t get fixed

A
  • Laser drift, wall vibrations from surroundings
  • Someone bumped it
  • Patient levelling and positioning off isocentre, large shifts from imaging
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14
Q

Optical Distance Indicator accuracy at isocentre

reasons for failure and what happens if it doesn’t get fixed

A

-ODI indicator may have
drifted/damaged/bumped

  • SSD checks would be incorrect
  • SSD setups would be systematically out
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15
Q

Light Field size

reasons for failure and what happens if it doesn’t get fixed

A
  • Light source not on collimator rotation axis
  • Light source may not be the correct SSD
  • Jaw calibration changed
  • Field size could be inconsistent depending on the SSD, border checks shows incorrect information
  • Jaw incorrect calibration can lead to all patient field size treated incorrectly
16
Q

Door Interlock/Beam on Indicator/lights and
audible indicator

reasons for failure and what happens if it doesn’t get fixed

A
  • Electronic component failure
  • Circuit board failure
  • Safety issue- someone can enter the room during treatment without the knowledge of operator
17
Q

Audio Visual

reasons for failure and what happens if it doesn’t get fixed

A
  • AV system failure
  • Power supply of AV system failure
  • Patient safety
  • Inability to coach RPM
18
Q

Australian Clinical Dosimetry Service (ACDS)

A
  • National dosimetry audit program
  • Commonwealth Government’s Australian Radiation Protection and Nuclear Safety Agency ARPANSA
  • primary standards dosimetry laboratory that provide chamber calibration
  • Institutions calibrate the linear accelerators using calibrated ionisation chamber under reference conditions
  • All relative dosimetry all relate back to reference condition
    Evaluate dosimetry under a range of conditions
    Level 1- basic reference condition
    Level 2- wedge factors, depth dose, field size, off axis,
    Level 3- end to end test
    (CT phantom -> planning -> R&V -> treatment delivery)
    include 3DCRT, IMRT, VMAT, FFF
19
Q

Treatment Planning Quality Assurance + tests include

A

✓Routinely performed (e.g. monthly QA using standardised plans)
✓Post Upgrades

List of tests include:
* Back up and Recovery
* CT data transfer- Demographics, Patient Orientation * CT density and geometry
* Patient Anatomy
* External beam revalidation
* Monitor Units Check
* Plan Transfer
* Patient Specific Quality Assurance (PSQA)

20
Q

Patient Specific Quality Assurance

A
  • Monitor Unit Calculation for 3DCRT
  • Excel spreadsheet manual dose calculation * AAPM TG 114
  • IMRT QA
  • Dose point measurement
  • 2D relative dose fluence maps
  • DQA for Tomotherapy
  • Cheese phantom for dose point
  • Film dosimetry for 2D fluence maps
21
Q

Patient Specific QA Equipment

A
  • MatrixX
  • Delta4
  • ArcCheck
  • Octavius
  • MapCheck
  • EPID
22
Q

Analysis of PSQA

A
  • Measured vs Calculated dose comparison
  • Validation of both mechanical and dosimetric uncertainties
  • Distance to agreement is a good parameter in the high dose gradient region but not so good in low dose gradient areas
  • 3%/3mm Gamma Pass Index Criteria are based on the combined mechanical and dosimetric uncertainty contribution to the measure dose
  • Dose to panel vs Dose to Patient
  • Higher probability of dose disagreement observed when: * Lower MU Efficiency
  • Plan Complexity
  • Evaluate your plan for potential for plan failure
23
Q

EPIQA

A
  • EPIQA is a commercial software that converts a dosimetric image acquired by an EPID into a dose map, and compare with a reference dose distribution from the TPS
  • EPIQA was specifically developed for Varian amorphous silicone a-Si500 EPID
  • The software can be utilised for verification of static and dynamically modulated fields
  • Dosimetry image conversion to dose is based on the GLAaS algorithm
  • Pre-Treatment verification tool- incapable of in vivo dose verification
  • Identify potential errors in the calculation of the in the dose delivery process