CT Simulation & Motion Management Flashcards

1
Q

what is QA

A

is the overall process which is supported by quality control activities.

QA encompasses all the planned and systematic actions needed to ensure that a product or service will meet the given requirements for quality. In radiation therapy, this involves a range of procedures, activities, actions, and staff groups to maintain the consistency and safety of the medical prescription

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what is QC

A

describes the actual mechanism and procedures by which one can assure quality

QC is a subset of QA and involves activities that impose specific quality on a process. It entails evaluating the actual operating performance characteristics of a device or system, comparing it to desired goals, and taking action on the difference. For instance, QC in radiation therapy might involve regular checks of linac output constancy, mechanical tests like the front pointer, safety tests with survey meters, and checks of meteorological equipment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

CT daily QA

A
  • alignments of lasers to gantry plane
  • CT number - water
  • image noise
  • spatial accuracy

Most likely RT would be responsible for the daily tests.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

CT monthly test

A
  • orientation of lasers (parallel and orthogonal to imaging plane)
  • spacing of wall lasers for patient localisation lasers to imaging scan plane
  • orientation of CT table relative to imaging scan plane
  • accuracy and reproducibility of digital indicators for vertical and longitudinal motion
  • CT number accuracy for different materials
  • 3D spatial accuracy

Typically performed by local physicist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what happens if Spatial Accuracy are out of tolerance?

A

tolerance is +/- 1mm

difference = CT scanned image of object dimension - actual object dimension

how to measure
- this should be verified by CT scanning, using a phantom of known dimensions
- this should be verified different scan protocols

why is it important
- RT planning relies on accurate reproducible representation pf the patient dimensions and shape including
- geometric miss of target - either under or over treating
- image distortion can lead to misleading in causing inappropriate dose dumping to the wrong area

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what happens if lasers are out of tolerance

A

tolerance : +/- 2mm

  • Treatment room lasers are well defined and precise localisation of the treatment isocentre, the CT must possess the same relationship to the CT image centre.
  • can affect the ability to identify skin marks and required for reproducible patient position for setup
  • accuracy needs to be comparable to treatment machines lasers
  • Contact Physics/relevant staff if the lasers are out of tolerance so they can be recalibrated ( this might require additional tools and checks such as alignment, tilt/skew/positioning and reference wall marks to be updated if required)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what happens if noise is out of tolerance? + how to perform/check

A
  • Should be performed for head and body phantoms
  • Check your phantom is placed in the centre of the imaging bore (you can use table height to find the centre quickly)
  • Manufacturer typically provide phantoms and software to
    automatically measure noise
  • image quality directly affects the ability to identify and delineate target volume and surrounding critical structures
  • this can impact treatment planning as suboptimal images may cause omission of target volume or inadvertent delineation of normal structures
  • noise is very sensitive parameter in overall imaging performance of scanner
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what happens if HU for water is out of tolerance

A
  • CT scanner is calibrated to give 0 HU for water, and the relationship between the relative electron density to CT numbers are mapped in the TPS (CT to ED curve or CT to density curve)
  • deviation may indicate equipment fault in beam hardening, or image reconstruction software issues
  • incorrect density corrected dose calculation are used in treatment planning, so incorrect CT numbers to density relationship can cause dose calculation errors
  • incorrect water HU will lead to incorrect relative HU
  • external definition also rely on accurate HU delineating the skin and air threshold
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

CT annual QA

A
  • table positioning
  • gantry tilt accuracy
  • scan localisation from scout
  • radiation profile width-slice collimation
  • CTDI - patient dose delivered
  • spatial resolution - high contrast resolution
  • contrast resolution - low contrast resolution
  • field uniformity

Typically performed by physicist at predetermined frequency or after service/repairs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

two fundamental sources of positioning error in dose delivery

A
  1. determination of the tumour position as a function of time

2.calibration of the spatial relation between the tracking coordinate system and the beam delivery coordinate system

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

MIP + advantages and disadvantages

A

maximum intensity projection =

advantages
- one 3DCT gives information that encompass the entire range of tumour motion and TIV delineation can be performed in a timely manner

limitations
- ITVs created using MIPs are smaller and may result in geometric miss compared to ITV delineation using the whole 10 phase 4DCBCT
- difficult to see if near motion - eg. mediastinum, chestwall or diaphragm
- cant be used if tumour is near a high density edge - structures will get blurred out
- any irregularity in breathing during 4DCT acquisition will result in post processing artifacts
- limited to contouring only - higher CT HU units than a regular CT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

limitations of 4DCT

A
  • largest uncertainties for small tumours with large amplitude of motion with short period of oscillation
  • longer scans can lead to increased motion artefacts
  • larger the velocity, increases the volumetric deviations - typically 4DCT overestimate the volume of tumour
  • contouring can also be performed on the MIP or average image or 10 phase 4DCT for the ITV definition of tumour excursion in all directions absolute volume and positioning deviations
  • gating systems rely on an the interpretation that the external signal and its periodicity are reflective on the motion of the underlying tumour
  • can be used in conjunction with other types of tracking technology to give real time tumour motion
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

SGRT advantages + disadvantages

A

advantages
- non ionising and non invasive
- high accuracy and resolution of 3D surfaces
- clinical trials postural visualisation
- patient feedback
- independent from linac gantry motion
- real time motion management
- gating and breath hold capability
- faceless mask option
- may not require SGRT on CT
- Faceless mask option (watch out for blink motions creating false gate

Disadvantages
- Equipment/Financial resources
- Additional training and increase of time

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

five (5) motion management strategies

A
  1. internal Target Volume (ITV) - any treatment of a target volume which encompasses the entire range of
    motion of the lesion.

2.Free-breathing Gating - any treatment where delivery of the beam is limited to a portion of the respiratory cycle as the patient breathes normally.

3.Breath-hold Gating - any treatment where the delivery of the beam is limited to a portion of the respiratory
cycle which is extended by the patient holding their breath. Note that this strictly refers to breath-hold gating as a motion management strategy, rather than a means of optimising tumour geometry (as is the case in most deep inspiration breath-hold breast treatments utilising tangential beams).

4.Mid Ventilation - any treatment where the target volume is defined using the time- weighted average
position of the tumour.

5.Tumour Tracking - any treatment in which the treatment beam is modified/repositioned to account for the motion of the target.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Phase based binning pros and cons

A

Pros
- The breathing cycle is diving into equal time points
- Closely depicts the actual movement over time
- Allows calculation of the mid ventilation phase

Cons
- If the patient has any inconsistent breathing patterns it leads to 4D CT artifacts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Amplitude based binning pros and cons

A

Pros
* Breaks down the breathing phase into equally spaced sections
according to the signal amplitude
* Overall artifacts are fewer when patient has irregular breathing
patter
* Max exhale phase can easily be reconstructed

Cons
* Not possible to read the actual movement of the tumour over time
* Not suitable for mid ventilation phase

17
Q

Limitations of RPM with 4DCT

A

*Longer scans can lead to increased motion artefacts
*Larger the velocity, increases the volumetric deviations-typically 4DCT overestimate the volume of tumour
*Contouring can also be performed on the MIP or average image or 10 Phase 4DCT for the ITV definition of tumour excursion in all directions absolute volume and positioning
deviations.
*Gating systems rely on an the interpretation that the external
signal and its periodicity are reflective on the motion of the underlying tumour.
*Can be used in conjunction with other types of tracking technology to give real time tumour motion.

18
Q

Real Time Positioning Management (RPM) + benefits and drawbacks

A

Gating using an external respiration signal using an infrared reflective plastic box serving as an external fiducial marker placed on the anterior abdominal surface.
Location is chosen to maximise AP motion

Benefits
* If using gating- Less straining for patients than breath hold
* Can be used for breath hold
* Minimise toxicity
* Enable dose escalation (SBRT treatment) highly conformal dosimetry
* Doesn’t use consumables (e.g. ABC)

Drawbacks
* Increase treatment time
* Surrogate for tumour movement
* What is the correlation between the marker motion and the tumour position?

19
Q

Commissioning the RPM on the Linac

A

Camera Calibration
- Accuracy of the camera determination of the amplitude of AP motion
- Limitation of optimal distance from camera
- Accuracy of the timescale

Camera use
- Connectivity and functionality with integrating the reference breathing trace
- Beam interrupt / beam hold

20
Q

Limitations of RPM

A
  • Gating systems rely on an the interpretation that the external signal and its periodicity are reflective on the motion of the underlying tumour.
  • Single point in space representing the patient’s setup- arch back.
  • Useful to verify the breathing periodicity and amplitude is regular is reproducible from CT
  • can help with the inter and intra fraction uncertainties, however
    regular imaging is sometimes also required to confirm the anatomy (e.g. CBCT or kV)
  • Additional types of tracking technology can be used to give real time tumour motion.
21
Q

Reasons why it fails QA for SGRT

A
  • Misalignment between treatment isocentre and CBCT isocentre
  • physics need to perform Iso-cal check
  • Couch rotation offsets from the treatment isocentre
  • verify with Winston-Lutz
  • Camera has been moved
  • Coordinate system
  • Thermal Drift – short and long term
  • Reproducibility
22
Q

phase based binning

A

Divides the respiratory cycle into distinct phases, such as inhalation, exhalation, and intermediate points

23
Q

Amplitude-Based Binning

A

Divides the respiratory cycle based on the position (amplitude) of the respiratory signal rather than the timing or phase.

24
Q

quality audit + rationale

A

systematic and independent examination to determine whether or not quality activities and results comply with planned arrangements and whether or not the arrangements are implemented effectively and are suitable to achieve the stated objectives

rationale - evaluate the need for improvement or corrective action if those standards are not met

25
Q

quality audits characteristics

A
  • should be regular and a form part of a quality feedback loop to improve quality
  • voluntary
  • regulatory
  • procedural or practical
26
Q

CT Legislative requirements

A

Radiation Shielding of premises
- Ensure adequate shielding based on workload
- Ensure no changes to shielding integrity
- installation of power point
- May involve Radiation Survey in the CT room
- Calculation for shielding requirements
- Carer/Comforter
- Only done in commissioning

27
Q

4D Motion Management 3 Different facets to consider

A
  1. 4D CT imaging- the acquisition of a sequence of CT image sets over a consecutive segments of a breathing cycle
  2. 4D treatment planning- designing treatment plans on a CT image sets obtained for each segment of a breathing cycle. E.g contouring ITV, determining maximum excursions
  3. 4D treatment delivery- delivery of a treatment plan by breath hold, abdominal compression or gated/continuous delivery over the entire breathing cycle.
28
Q

Some examples of commercially available motion management systems

A
  • Varian RPM- gating and breath hold
  • Elekta Active breath Control
  • Accuracy Cyberknife Synchrony
  • Novalis Brainlab ExactTrac
  • Philips Bellows System
  • ANZAI belt
  • Calypso RF beacons
  • Abdominal Compression
29
Q

4DCT + 2 methods

A

Low pitch helical CT is acquired while the patient breathes normally. The breathing pattern is required to be reproducible and stable trace can be establish. IF motion is irregular, it is difficult to ascertain the respiratory trace from the breathing cycle

  • phased binning
  • amplitude binning
30
Q

phased binning + pros and cons

A

Phase method which is based on the percentage of the breathing cycle

Pros
- The breathing cycle is diving into equal time points
- Closely depicts the actual movement over time
- Allows calculation of the mid ventilation phase

Cons
- If the patient has any inconsistent breathing patterns it leads to 4D CT artifacts

31
Q

amplitude binning + pros and cons

A

User defines the min and max limits between which the CT acquisition is dependent on the absolute position of the marker regardless of the phase of breathing.

Pros
- Breaks down the breathing phase into equally spaced sections according to the signal amplitude
- Overall artifacts are fewer when patient has irregular breathing patter
- Max exhale phase can easily be reconstructed

Cons
- Not possible to read the actual movement of the tumour over time
- Not suitable for mid ventilation phase

32
Q

RPM Quality Assurance

A

As with all QA procedures, appropriate tests should be performed after any hardware or software changes. This includes all equipment that interfaces with the RPM system, such as linac or CT
- Ensure the reconstructed 4D images are free of artefacts
- Accuracy of the camera determination of the amplitude of AP motion for treatment and CT
- Accuracy of the determination of the excursion of tumour motion
- Accuracy of the reconstructed MIP image for determination of excursion of tumour motion

33
Q

SGRT commissioning tests

A

*Connectivity to R&V system
* Field of view – occlusion with gantry rotation
* Spatial Drift and Reproducibility
* Warm up period
* Localisation accuracy during warm up
* Reproductivity of spatial accuracy
* Static shifts accuracy (x,y,z and rotation)
* Dynamic Localization (using a motion controlled phantom)
* Latency and frame rate
* Dose Accuracy – interruptions to dose delivery accuracy * Drift over time (short and long term)
* Setup the isocentre of the SGRT using CBCT, kV & MV imaging
* Accuracy of applied shifts to treatment couch (coordinate system e.g. Varian vs IED 1217)
* End to end testing
* Standard operating procedures and guidelines

34
Q

SGRT Routine Daily QA

A
  • Safety - Check interlocks are functional
  • Static Localisation
  • Positioning accuracy - the isocentre of the SGRT using CBCT and kV MV imaging
  • Accuracy of applied shifts to treatment couch
  • Needs to be robust, quick and easy to setup
  • Static Localisation Accuracy – Performed by RT
  • Relative Camera Position - performed by RT
  • Reviewed by physicist
35
Q

Why SGRT Daily QA fail?

A
  • Misalignment between treatment isocentre and CBCT isocentre
  • physics need to perform Iso-cal check
  • Couch rotation offsets from the treatment isocentre
  • verify with Winston-Lutz
  • Camera has been moved
  • Coordinate system
  • Thermal Drift – short and long term
  • Reproducibility
36
Q

monthly SGRT QA

A
  • Safety
  • Static and Dynamic Localisation
  • Include calibration and chamber measurement
  • Performed by physicist
  • Typically, best combined with other Linac QA
    • WL
    • Integrate with 6DOF couch QA
37
Q

SGRT Annual QA

A
  • Visual inspection of cameras
  • Check the coordinate system
  • Check archive and restore functionality
  • Perform plate calibration (if required) and follow daily QA capture
  • Perfom static localisation accuracy test
  • Perform beam gating functionality test and dose measurement using test plans
  • Perform dynamic localisation accuracy using 3D-3D image matching of calibration cube
  • Perform cube calibration
  • System drift after short term power loss