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Respiratory Pharma > Treatment Of Viral And Fungal Pneumonia > Flashcards

Treatment Of Viral And Fungal Pneumonia Flashcards

1
Q

Drugs inhibit uncoating and replication of viral RNA

A

Amantadine
Rimantadine

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2
Q

Drugs treat influenza A infections within the first 48 hours and used for prophylaxis during flu season

A

Amantadine
Rimantadine

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3
Q

From their adverse effects are
CNS effects
GI dysfunction

A

Amantadine
Rimantadine

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4
Q

Drugs that inhibit neuraminidase enzyme

A

Zanamivir
Oseltamivir( tamiflu)

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5
Q

Used in treatment and prophylaxis of acute uncomplicated influenza infection
Effective against both A and B

A

Zanamivir
Oseltamivir

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6
Q

From its adverse effects are
Abdominal pain and GI dysfunction

A

Oseltamivir

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7
Q

Drug may cause bronchospasm

A

Zanamivir

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8
Q

Drug inhibit viral RNA polymerase and it is a prodrug

A

Ribavirin

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9
Q

Drug used in treatment of
RSV
HCV
HBV
In combination with interferon alpha

A

Ribavirin

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10
Q

Drug may cause
Hemolytic anemia
Teratogenicity in pregnancy

A

Ribavirin

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11
Q

Drug inhibits the activity of viral DNA polymerase

A

Acyclovir

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12
Q

Used to treat HSV type 1 and 2

A

Acyclovir

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13
Q

Used in treatment of Epstein Barr virus

A

Acyclovir

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14
Q

Treat varcilla zoster virus

A

Acyclovir

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15
Q

Treat cytomegalovirus

A

Acyclovir

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16
Q

May cause well tolerated nausea, diarrhea and headache

A

Acyclovir

17
Q

May cause nephrotoxicity and neurotoxicity reversible if given I.V

A

Acyclovir

18
Q

Drug that is similar to acyclovir but highly active against CMV

A

Gancyclovir

19
Q

Adverse effects of gancyclovir are

A

Neutropenia ( reversible)
Thrombocytopenia

20
Q

.

Is a drug of choice for systemic blastomycosis

A

Itraconazole

21
Q

Drug of choice for systemic candidiasis and cryptococcal meningitis

A

Fluconazole

22
Q

Drug of choice for invasive aspergillosis

A

Voriconazole

23
Q

Inhibitor of nucleic acid synthesis

A

Flucytosine

24
Q

Inhibit nucleic acid synthesis

A

Flucytosine

25
Q

May cause
- Depression of bone marrow at high doses
- Hair loss

A

Flucytosine

26
Q

Inhibit beta glucan

A

Echinocandines ( caspofungin)

27
Q

Used in severe invasive aspergillosis

A

Caspofungin

28
Q

Used in treatment of esophageal candidiasis

A

Caspofungin

29
Q

May cause skin rash or itching

A

Caspofungin

Respiratory Pharma (2 decks)

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