Treatment

Question 1

What are the treatment options for SCLC?

Answer 1

• Chemotherapy

- Palliation

Question 2

What are the treatment options for NSCLC?

Answer 2

• Surgery
• Radical radiotherapy
• Palliation - symptomatic, radiotherapy, chemotherapy

Question 3

What is the management for malignant mesothelioma?

Answer 3

• Pemetrexed and cisplatin chemotherapy can improve survival
• Surgery
• Pleurodesis and indwelling intra-pleural drain may help

Question 4

What is the staging and treatment of NSCLC?

Answer 4

• Lobectomy - T1a-b, N0, M0
• Radical radiotherapy - Stage I, II, III
• Chemotherapy +/- radiotherapy - more advanced disease, may be targeting EGFR (atuximab)

Question 5

What is the staging and treatment of SCLC?

Answer 5

• Consider surgery for limited stage disease
• Chemotherapy +/- radiotherapy if well enough
• Palliation - radiotherapy for bronchial obstruction, haemoptysis etc.
• Endobronchial therapy: tracheal stenting, cryotherapy, laser, brachytherapy
• Pleural drainage/pleurodesis for symptomatic pleural effusions
• Analgesia, steroids, anti-emetics, bronchodilators