Transport in Animals Flashcards

1
Q

why is there a need for specialised systems in multicellular organisms?

A
  • high metabolic demand=diffusion alone x effective
  • ↓SA:V in large multicellular organisms=↓SA for absorption
  • enzymes/hormones need to be transported
  • food digested has to be transported to every cell
  • waste products removed from every cell and transported to excretory system
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2
Q

open vs closed circulatory system

A

open eg. insects+molluscs:
* few vessels
* pumped from heart into body cavity (haemocoel)
* low pressure
* direct contact with blood and cells
* open ended vessel returns fluid to heart
* haemolymph transports nutrients/waste
* heart in thorax+abdomen
* no steep conc. gradient
* x meet demand of organism
closed eg. annelids (worms), vertebrates:
* blood enclosed in vessels=x direct contact with cells
* heart pumps under pressure
* substances enter and leave by diffusion
* bld. flow adjusted (widening/narrowing)
* contain bld. pigment for gases
* single or double

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3
Q

single vs double circulatory system

A

single eg. fish, annelid
* bld. travels once through heart
* bld. passes through 2 srts of capillaries to exhange gases, nutrients, waste
* pressure drops limits efficiency (exception fish=cold blooded, weight supported by water & countercurent
double eg. birds, mammals
* blod. travels twice through heart
* most efficient
* high pressure
* fast flow
* effective for active animals that manitin body temp.

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4
Q

layers of blood vessels

A
  • tunica externa/adventitia
  • tunica media
  • tunica intima
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5
Q

histology of vessels

A
  • elastic fibres:provide flexiblity, stretch, recoil, thin+interwoven with collagen fibres (prevent tearing), made of elastin
  • collagen fibres: high tensile strength, structural support, some flexibility (fibrous protein)
  • smooth muscle: contracts/relaxes=constricts/dilates artery
  • endothelium:inner lining of cells, folds/unfolds, single layer, smooth=↓ friction
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6
Q

histology of arteries

A
  • lined with endothelium (tunica intima)
  • thick muscular (tunica media) walls=withstand+maintain ↑ pressure
  • wall has smooth muscle (tunica externa)
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7
Q

structure+function of arterioles

A
  • diameter (<100 μm)
  • come from an arterial branch (between small arteries+capillaries)
  • lined with smooth muscle (less elastin)=allows diameter to be controlled by nerves+hormones
  • dilate/constrict=control blood flow
  • smooth muscle contracts=vasoconstriction+↑ pressure&resistance
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8
Q

structure and function of capillaries

A
  • diameter=same as rbc=only one can pass at a time=slows down bld. flow=allows fro diffusion to occur
  • one cell thick=thin walls=short diffusion path
  • links arterioles+venules
  • gaps b/w flattened endothelial cells (except brain)=leaky walls=allows substances to enter/exit
  • arranged into capillary beds=large SA
  • site of exchange+diffusion of materials b/w cells+bld as ↓bld. flow
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9
Q

structure+function of venules

A
  • thin walls+little smooth muscle
  • receive bld from capillaries
  • loads join to form a vein
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10
Q

structure+function of veins

A
  • diameter (<30μm-2.5cm)
    *carry bld away from cells, towards heart
    *↓pressure, no pulse=can act as large resrvoirs
  • deoxygenated bld except from pulmonary+umbilical vein
  • outermost layer=lots of collagen but little elastic fibres
  • wide lumen+smooth endothelium
  • valves=folds of innermost layer+strengthened by fibrous tissue=prevent back flow, only found in medium/small veins
  • close to muscles in limbs=muscle contracts=press on bld in veins+push it up
  • breathin movements in chest=act as a pump to pull bld up
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11
Q

Components and functions of blood

A
  • components
    Plasma (mostly water, transports substances in solution), rbcs (carry O2), wbcs (immunity), platelets (clotting)
  • functions of bld
    Transports O2, CO2, nutrients from digestion, waste from excretion, hormones, etc
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12
Q

Tissue fluid: how is it made+role

A
  • has same composition as plasma but it has no rbcs, less proteins, less wbcs
  • formation
    At the arteriole end of capillaries:
    A high hydrostatic pressure, exerted by the force of the heart pumping, forces fluid out of capillaries.
    This forms tissue fluid surrounding body cells.
    At the venule end of capillaries:
    The hydrostatic pressure is lower.
    Proteins in blood exert a high oncotic pressure in capillaries.
    The water potential is lower in capillaries than in tissue fluid due to fluid loss.
    Some tissue fluid moves back into capillaries by osmosis.
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13
Q

Lymph: composition+formation+transport

A
  • same as tissue fluid but has less oxygen+nutrients, more fatty acids, more wbcs
  • the tissue fluid that doesn’t reenter capillaries=drains into lymph vessels=forms lymph
  • transported through lymph vessels by muscle contractions
  • lymph passes lymph nodes=filter pathogens
  • lymph eventually returns to bld
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14
Q

Structure of heart

A
  • separate pumping mechanisms
    Bld pressure drops in lungs as it flows in capillaries
    Single pump=slows bld flow to body cells
    2 pumps increase pressure before bld circulates
  • valves
    AV valves=tricuspid valve (right)+bicuspid/mitral valve (left)
    Semi-lunar valves
    Found in aorta and pulmonary artery
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15
Q

Cardiac cycle

A
  • atrial systole
    Atria contract (ventricle relax)=up atrial pressure=AV valve open=bld flows into ventricles
  • ventricular systole
    Ventricles contract (atria relax)=up ventricular pressure=semilunar valves open+AV valves close=bld flows into arteries (aorta+p.artery)
    -diastole
    Ventricles+atria relax=SL valves close=bld flows passively into atria
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16
Q

Cardiac output definition

A

Vol. of bld pumped by one ventricle per minute

17
Q

Cardiac output equation

A

Cardiac output=heart rate x stroke vol
Heart rate=heart beats per minute
Stroke vol=vol. of bld pumped by left ventricle during ventricular systole

18
Q

How heart beat is initiated+coordinated

A
  • SAN=initiates heartbeat=sends wave of excitation=atria contract
  • layer of collagen fibres prevent wave to immediately reach AVN=allows ventricles to fill w bld
  • AVN spreads wave of excitation to Bundle of His=sends wave to heart’s apex
  • Purkyne fibres=branch off bundle of His=cause ventricles to contract from the bottom up
19
Q

How does Hb transport O2?

A

Oxygen binds to haem grp in haemoglobin which is in rbcs=forms oxyhaemoglobin=transported via bld to respiring tissues=when it reaches, oxygen dissociates from haemoglobin (reversible reaction)
Higher pO2=Hb has a high affinity for O2=binds to it (opposite for low pO2)
Hb changes shape when it binds to one O2 molecule =easier to bind to other oxygen molecule but when Hb is too saturated=harder for oxygen to bind

20
Q

Fetal vs adult Hb

A
  • fetus needs to obtain oxygen from the mother’s blood.
  • fetal Hb therefore has a higher oxygen affinity than the adult Hb found in the mother’s bld=allows the oxygen to dissociate from the mother’s Hb, and bind with Hb in the fetal blood=ensuresfetus gets enough oxygen to survive while it develops.
21
Q

Bohr effect

A
  • high pCO2 at respiring tissues=causes Hb to release oxygen
  • needed bc active tissues require lots of oxygen from bld
  • ODC shifts to the right
22
Q

How is CO2 transported?

A
  • in rbc
    CO2 attaches to a Hb chain=forms carbaminoHb (10-20%)
  • **in active tissues=high pCO2)
    Rest reacts with water= CO2+H2O <—> H2CO3 —> H+ + HCO3- (catalysed by carbonic anhydrase)
    HCO3- diffuses into plasma, H+ reacts with Hb=forms reduced Hb/haemoglobinic acid=prevents bld becoming too acidic (Hb acts as a buffer)
    chloride shift=Cl- in plasma diffuse into rbc=maintains charge balance
  • in the lungs
    Low pCO2=HCO3- + H+ react to form H2O+CO2=breathed out