Transport Across the Membrane Flashcards
Why is the cell membrane described as a fluid-mosaic?
Fluid because the phospholipids are constantly moving. Mosaic because all the proteins in the membrane create a mosaic pattern.
What are the main components of the cell membrane?
phospholipids
cholesterol
glycoproteins and glycolipids
other proteins like carrier and channel proteins.
What do channel and carrier proteins do?
They allow large molecules and ions to pass through the membrane.
What does cholesterol do?
It controls the fluidity of the membrane.
How does cholesterol control the fluidity of the membrane?
When the temperature increases, the cholesterol binds to the hydrophobic tails of the phospholipids causing them to pack closely together so the membrane does not become too fluid. When it is cold it lies between the phospholipids molecules so the membrane doesn’t freeze and crack.
What is diffusion?
The net movement of particles from an area of high concentration to an area of low concentration.
What substances move across the membrane via diffusion?
small, lipid-soluble substances
Why does diffusion decrease over time?
As diffusion happens, the concentration gradient decreases meaning the rate of diffusion decreases over time.
What three factors affect the rate of diffusion?
- Concentration gradient
- The thickness of the membrane
- The surface area of the mebrane
How does the concentration gradient affect the rate of diffusion?
The higher the concentration gradient, the higher the rate of diffusion.
How does the thickness of the membrane affect the rate of diffusion?
The thicker the membrane, the lower the rate of diffusion as the diffusion distance increases.
How does the surface area of the membrane affect the rate of diffusion?
The higher the surface is, the higher the rate of diffusion.
What is facilitated diffusion?
The movement large particles and ions down a concentration gradient using channel and carrier proteins.
How do carrier proteins move large molecules across the membrane?
A large molecule attaches to one end of the channel protein. The protein changes shape which allows the large molecule to move into the opposite side of the membrane.
How do channel proteins move charged molecules across the membrane?
They form pores in the membrane, which allow charged particles to diffuse down a concentration gradient.