transport across a membrane Flashcards
describe the fluid mosaic model
A phospholipid bilayer containing:
Channel/carrier proteins
Cholesterol
Glycolipid
Glycoprotein
fluid as phospholipids and proteins are constantly moving in their layer.
mosaic as contains multiple types of proteins distributed unevenly in the membrane.
Describe the function of cholesterol
cholesterol controls membrane fluidity.
the more cholesterol, the less fluid and permeable the membrane becomes.
Describe osmosis
The passive net movement of water molecule, from an area of higher water potential to area of lower water potential (=down a water potential gradient), across a partially permeable membrane.
-Requires an aquaporin in cell membrane
Describe the function of glycoproteins/glycolipids
glycoproteins/glycolipids/proteins are involved in cell recognition) and cell signalling due to their specific tertiary structure that is complementary to one molecule/ binding site
List the factors that affect the rate of diffusion
1.Surface area
2.oncentration gradient
3. Diffusion distance:
ficks law
rate of diffusion=surface area x concentration gradient /diffusion distance
- Temperature
- number of channel/carrier proteins in the phospholipid bilayer.
- Describe Facilitated diffusion
- The passive net movement of polar/large molecules/ions down a concentration gradient (high->low), across a partially permeable membrane
Requires: channel or carrier protein with complementary binding site.
- Describe Active transport
- The active movement of molecules/ions against a concentration gradient (low->high), across a partially permeable membrane.
Requires: carrier proteins with complementary binding sites and the release of energy from the hydrolysis of ATP -> ADP and P.
Describe exocytosis
Vesicles contain large volume of molecules (eg enzymes/ antibodies ect)
Vesicles fuse with cell membrane
Contents of vesicle released into blood/extracellular space.
[Note:
Bulk movement that requires energy released from the hydrolysis of ATP into ADP and P. ]
Describe Endocytosis
1.Large concentration/volumes of molecules
outside the cell.
2. Engulfing, by cell membrane pulling inwards, forms a vesicle around molecules.
3. Vesicle remains inside cell cytoplasm.
[Note:
A Bulk movement that requires energy released from the hydrolysis of ATP into ADP and P. ]