Transport Flashcards
2 main types of transport:
active and passive
Passive
movement across a membrane without using energy
Active
energy dependent
TYpes of passive transport
SIMPLE DIFFUSION and faccilitated diffusion
osmosis
SIMPLE DIFFUSION
movement of substance across membrane from area of high to low concentration
Small, non-polar
O2, CO2
Small, uncharged polar
Water (slightly)
FACILITATED DIFFUSION
diffusion has to be helped by proteins in the membrane.
what are TRANSPORT PROTEINS
are integral membrane proteins and come in 2 types:
CHANNEL PROTEINS
CARRIER PROTEINS
aquaporin (type of channel protein)
CHANNEL PROTEINS
form hydrophilic pathways in the membrane so H2O and some ions can pass
CARRIER PROTEINS
also form passageways, but bind to specific solutes. ex: glucose
these are specific which allows for tight control. ex: the glc carrier protein won’t bind fructose.
OSMOSIS
passive diffusion of water across membrane
water always diffuses from an area of low solute concentration to an area of higher solute concentration.
osmosis can cause cells to swell or shrink
hypertonic
has a higher concentration of solutes (and therefore a lower concentration of water) than cell’s cytoplasm, causing water to move out of the cell, leading to shrinkage
hypotonic
lower concentration of solutes (and therefore a higher concentration of water) compared to cell’s internal environment. This difference in solute concentration causes water to move into the cell, potentially leading to swelling or bursting.
PRIMARY Active Transport
molecular actice transport
pumps that move positively charged ions across membranes
ex: Calcium pump moves Ca2+ from cytosol to the cell exterior ex: sodium-potassium pump pushes 3 Na+ out of cell and 2 K+ into the cell
This creates unequal charge distribution (more + on outside of cell) and we create an electrochemical gradient. This is stored potential energy
Bulk transport
movement of large molecules using vesicles
exocytosis, endocytosis
Exocytosis
a vesicle fuses with the cell membrane are released and its membrane becomes aprt of teh cell
endocytosis
the cell membrane surrounds a per of the exterior environment and buds off as a vesicle
types of endocytotsis
receptor mediated endocytosis
phagocytosis
pinocyotist
receptor mediated endocyosis
The receptors on the membrane have a specific shape that matches the target molecule (like hormones, nutrients, or even viruses).
After the receptor binds to the specific molecule, clathrin (a protein) forms a coated pit, helping to form the vesicle.
The vesicle buds off the membrane, detaches, and transports the cargo into the cytoplasm.
Phagocytosis
cell engulfs large particles, such as debris, foreign substances, or microorganisms (like bacteria or viruses). It’s a crucial process for immune cells, like macrophages and neutrophils.
cell extends its pseudopodia (temporary projections of the cytoplasm) around the particle.
The pseudopodia fuse, enclosing the particle in a vesicle called a phagosome.
The phagosome then fuses with a lysosome, where the contents are digested by enzymes.
Pinocytosis (Cell Drinking
cell engulfs small amounts of extracellular fluid, along with dissolved solutes
The cell membrane invaginates (folds inward), forming small vesicles that take in extracellular fluid and dissolved substances.
Unlike receptor-mediated endocytosis, there is no specific recognition of the substances being internalized.
The vesicle forms, and then it buds off the membrane to transport the fluid into the cytoplasm.