Transplant Flashcards
antithymocyte globulin
ATGAM-Equine
Thymoglobulin-Rabbit
binds to antigens on T-lymphocytes; depletes mature and immature T-lymphocytes
basiliximab
Simulect
IL-2 antagonist
mycophenolate mofetil
CellCept
antiproliferative; inhibits T-lymphocyte proliferation by altering purine synthesis
mycophenolic acid
Myfortic
antiproliferative; inhibits T-lymphocyte proliferation by altering purine synthesis
tacrolimus
Prograf, Astagraf XL, Envarsus XR
CNI
cyclosporine, modified
Neoral, Gengraf
CNI
cyclosporine, non-modified
SandIMMUNE
CNI
everolimus
Zortress, Afinitor
mTOR kinase inhibitor
sirolimus
Rapamune
mTOR kinase inhibitor
belatacept
Nulojix
binds to CD80 and CD86 on antigen presenting cells to block t-cell costimulation