Autoimmune Flashcards

1
Q

methotrexate SC injection

A

Otrexup, Rasuvo

non-biologic DMARD

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2
Q

methotrexate PO

A

Rheumatrex, Trexall

non-biologic DMARD

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3
Q

leflunomide

A

Arava

non-biologic DMARD

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4
Q

tofacitinib

A

Xeljanz

non-biologic DMARD

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5
Q

rituximab

A

Rituxan

depletes CD20 B cells
many indications

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6
Q

anakinra

A

Kineret

IL-1 antagonist
RA

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7
Q

abatacept

A

Orencia

inhibits T-cell activation by binding to CD80 and CD 86
RA

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8
Q

tocilizumab

A

Actemra

IL-6 antagonist
RA

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9
Q

belimumab

A

Benlysta

IgG1-lambda monoclonal antibody, B-lymphocyte stimulator (BLyS)-specific inhibitor
lupus

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10
Q

glatiramer acetate

A

Copaxone, Glatopa

immune modulator
MS

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11
Q

interferon beta-1a

A

Avonex, Rebif

MS

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12
Q

interferon beta-1b

A

Betaseron, Extavia, Betaconnect

MS

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13
Q

peginterferon beta-1a

A

Plegridy

MS

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14
Q

teriflunomide

A

Aubagio

oral immune modulator
MS

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15
Q

fingolimod

A

Gilenya

oral immune modulator, sphingosine 1-phosphate receptor modulator
MS

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16
Q

dimethyl fumarate

A

Tecfidera

oral immune modulator
MS

17
Q

dalfampridine

A

Ampyra

potassium channel blocker - to improve walking in MS

18
Q

natalizumab

A

Tysabri

monoclonal Ab
MS and CD

19
Q

alemtuzumab

A

Lemtrada

humanized monoclonal Ab
MS