Transplant

Question 1

Post-lung transplant patient with persistent chest tube air leak in the early postop period (couple of days), be suspicious for

Answer 1

Bronchial dehiscence
(diagnose with bronchoscopy)

Question 2

HLA matching is unnecessary for liver transplantation because the liver has its own

Answer 2

Innate immune system

Question 3

What are the two organ systems where HLA matching is vital for success?

Answer 3

Kidney and BMT.
HLA-A, -B, -DR loci.

Question 4

Common side effects:
Nephrotoxicity
Neurotoxicity
HTN
Gingival hyperplasia
Hirsutism

Answer 4

Cyclosporine

Question 5

Common side effects:
Nephrotoxicity
Neurotoxicity
Alopecia
Diabetogenic
HTN

Answer 5

Tacrolimus

Question 6

Common side effects:
Hepatotoxicity
Bone marrow suppression
Leukopenia

Answer 6

Azathioprine

Question 7

Common side effects:
Nausea
Diarrhea
Hepatotoxicity
Leukopenia

Answer 7

Mycophenolate mofetil

Question 8

Common side effects:
Anemia
Hyperlipidemia
Thrombocytopenia

Answer 8

Sirolimus

Question 9

Management of a lymphocele that occurs post renal transplant

Answer 9

1. percutaneous drainage
2. laparoscopic vs. open marsupialization or fenestration to establish peritoneal communication.