Transmitter Systems

Question 1

Name the 3 catecholamines

Answer 1

Dopamine
Epinephrine
Norepinephrine

Question 2

Catecholamine receptors are:

a) ionotropic and metabotropic
b) ionotropic only
c) metabotropic only

Answer 2

c) metabotropic only

Question 3

Where are the catecholamine receptors made?

Answer 3

Discrete nuclei in brainstem and midbrain

Question 4

T or F: catecholamine release has broad projection over the brain

Answer 4

T

Question 5

Where is dopamine made?

Answer 5

substantia nigra

ventral tegmental area

Question 6

Cells no longer make which NT to result in Parkinson’s disease?

Answer 6

dopamine

Question 7

T or F: cell that make dopamine in the substantia nigra look black

Answer 7

T

Question 8

T or F: drugs that kill off dopamine producing neurons will result in Parkinson’s disease symptoms

Answer 8

T

Question 9

Dopamine made in which part of the brain is highly involved in the reward system?

Answer 9

VTA - ventral tegmental area

Question 10

T or F: addictive substances decrease dopamine release out of VTA

Answer 10

F - it INCREASES dopamine release out of VTA

Question 11

Where is norepinephrine made?

Answer 11

locus coeruleus

Question 12

T or F: norepinephrine projects widely throughout the brain

Answer 12

T

Question 13

The sympathetic or parasympathetic system is activated norepinephrine?

Answer 13

Sympathetic

Question 14

What response does the sympathetic nervous system control?

Answer 14

Fight or flight

Question 15

What response does the parasympathetic NS control?

Answer 15

Rest and digest

Question 16

Where is epinephrine made?

Answer 16

medullary epinephrine neurons

Question 17

T or F: epinephrine projects widely throughout the brain

Answer 17

F

Question 18

T or F: noepinephrine and epinephrine have the same receptors

Answer 18

T

Question 19

T or F: adrenaline has a weak effect on the peripheral NS

Answer 19

F - has a STRONG effect on periphery

Question 20

Which AA precursor does serotonin come from?

Answer 20

Tryptophan

Question 21

What is another name for serotonin receptors?

Answer 21

5HT receptors

Question 22

T or F: most serotonin receptors are ionotropic

Answer 22

F - most are metabotropic

Question 23

Where is serotonin made?

Answer 23

Raphe nuclei

Question 24

T or F: serotonin has broad projections throughout the brain

Answer 24

T

Question 25

Where is histamine made?

Answer 25

tuberomammillary nucleus of hypothalamus

Question 26

T or F: histamine is broadly projected throughout the brain

Answer 26

T

Question 27

T or F: histamine receptors are all ionotropic

Answer 27

F - all are metabotropic