Transmitter Systems Flashcards
Name the 3 catecholamines
Dopamine
Epinephrine
Norepinephrine
Catecholamine receptors are:
a) ionotropic and metabotropic
b) ionotropic only
c) metabotropic only
c) metabotropic only
Where are the catecholamine receptors made?
Discrete nuclei in brainstem and midbrain
T or F: catecholamine release has broad projection over the brain
T
Where is dopamine made?
substantia nigra
ventral tegmental area
Cells no longer make which NT to result in Parkinson’s disease?
dopamine
T or F: cell that make dopamine in the substantia nigra look black
T
T or F: drugs that kill off dopamine producing neurons will result in Parkinson’s disease symptoms
T
Dopamine made in which part of the brain is highly involved in the reward system?
VTA - ventral tegmental area
T or F: addictive substances decrease dopamine release out of VTA
F - it INCREASES dopamine release out of VTA
Where is norepinephrine made?
locus coeruleus
T or F: norepinephrine projects widely throughout the brain
T
The sympathetic or parasympathetic system is activated norepinephrine?
Sympathetic
What response does the sympathetic nervous system control?
Fight or flight
What response does the parasympathetic NS control?
Rest and digest
Where is epinephrine made?
medullary epinephrine neurons
T or F: epinephrine projects widely throughout the brain
F
T or F: noepinephrine and epinephrine have the same receptors
T
T or F: adrenaline has a weak effect on the peripheral NS
F - has a STRONG effect on periphery
Which AA precursor does serotonin come from?
Tryptophan
What is another name for serotonin receptors?
5HT receptors
T or F: most serotonin receptors are ionotropic
F - most are metabotropic
Where is serotonin made?
Raphe nuclei
T or F: serotonin has broad projections throughout the brain
T
Where is histamine made?
tuberomammillary nucleus of hypothalamus
T or F: histamine is broadly projected throughout the brain
T
T or F: histamine receptors are all ionotropic
F - all are metabotropic
