transmission of genetic diseases Flashcards
what are genetic diseases caused by
single genes
what are the 4 major types of genetic diseases
autosomal dominant, autosomal recessive
passed by both carriers,
X linked dominant ,
or X linked recessive
what genders are equally likely to exhibit autosomal disease
male and female
what genes can fathers not pass to their sons
x linked
what is gender determined embryonically by
SRY gene on the Y
chromosome.
embryocytes with a y become which gender
male
embryocytes with a x become which gender
female
describe mode of inheritance
the inherited patterns through the generations of a family
define consanguinity
inbreeding
what is inbreeding
mating of two related individuals
what are the offspring of inbreeding termed as
inbred
what do the proportion of shared genes between 2 related individuals depend on
closeness of the biologic
relationship
what risk does inbreeding dramatically increase the reoccurrence of
recessive disorders
offspring of marriages of first cousins who are affected by genetic diseases are doubled that of
general population