Translation Flashcards

0
Q

Start Codon

A

AUG “Met”

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1
Q

Stop codons

A

UGA, UAG, UAA

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2
Q

Wobble hypothesis

A

codon, anticodon pairing follows the traditional rules for the first two bases, but then is less stringent for the third/ last base

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3
Q

Enzyme involved with tRNA charging

A

amino acyl tRNA synthase (uses 2 P-P bonds)

“what really reads the genetic code”

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4
Q

Why is methionine always the first protein?

A

Only complex that can bind initially to the P site

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5
Q

What mechanism do antibiotic macrolides target?

A

block the elongation tunnel at the top of ribosomes to stop proteins form coming out

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