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Blood Bank - Clinical Rotation > Transfusion reactions > Flashcards

Transfusion reactions Flashcards

1
Q

Excess volume causes high RAP & pulmonary edema

A

TACO

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2
Q

Ab from plasma react with recipient lung tissue –> neutrophil infiltration, inflammation, and pulmonary edema

A

TRALI

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3
Q

Allergens from blood crosslink IgEs present on recipient mast cells
- degranulate HM
- Symptoms

A

Allergic TR

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4
Q

Ab binds recipient WBC and stimulates cytokine release; combined cytokines

A

FNHTR - Febrile non-hemolytic TR

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5
Q

IgM binds RBCs and activates complement
- RBC lysis and some phagocytosis to kill RBCs

A

Acute hemolytic TR

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6
Q

Acute pulmonary edema

A

TACO

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7
Q

Acute respiratory distress syndrome
Pulmonary Edema

A

TRALI

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8
Q

Hives, itching, occasionally anaphylaxix

A

Allergic TR

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9
Q

Fever, chills, high respiratory rate, anxiety, high or low BP

A

Febrile

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10
Q

Fever, chills, hypotension, hemolysis, renal damage

A

Acute HTR

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11
Q

Prevent by slow transfusion

A

TACO

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12
Q

Prevent by NOT accepting plasma

A

TRALI

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13
Q

Prevent by washed cellular components

A

Allergic TR

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14
Q

Prevent by Leukocyte reduction

A

Febrile

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15
Q

Prevent by TS and match

A

Acute HTR

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16
Q

Recipient has anti-ABO IgM in plasma that reacts with donor RBCs

A

Acute HTR

17
Q

Blood product contains anti WBC Ab and cytokines

A

Febrile

18
Q

Blood product contains allergens for that individual

A

Allergic TR

19
Q

Blood product contains anti-HLA Ab and anti-neutrophil Ab

A

TRALI

20
Q

Blood product volume

A

TACO

21
Q

Blood components are irradiated with gamma radiation to protect from

A

GVHD

22
Q

Patients with thrombocytopenia or abnormally functioning platelets

A

Platelet Transfusions

23
Q

______ components are prepared from one donor and must contain a minimum of 3 x 10(11) platelets.

A

Plateletpheresis

24
Q

Anticipated increases in platelet count: ___________

A

30,000 to 60,000/uL
(From Plateletpheresis)

25
Q

If the 10 minute increment platelet count increase is less than 50% of that expected on two occasions, the patient is considered _____

A

refractory

26
Q

Positive platelet XM and/or positive HLA antibody screen is considered evidence of ________

A

alloimmunization

27
Q

Washed RBCs are for

A

IgA deficient patients (Anaphylactic TR)

28
Q

Leukocyte-Reduced RBCs are used to reduce

A

HLA allo
CMV transmission
Febrile HTR
GVHD

Blood Bank - Clinical Rotation (17 decks)

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