Transfusion Medicine Flashcards
What is the universal donor type for red cells vs. plasma?
- Red cells = O negative
- Plasma = AB
Pt is chronically ill and symptomatically anemic (SOB, chest pain, tachy) with Hgb <7, what do you transfuse?
1 unit of red cells –> anticipate Hgb ↑ 1
Non-trauma patient has significant chronic coagulopathy; what do you transfuse?
Give 1 unit of FFP
Pt needs emergent warfarin reversal (i.e., elderly pt w/ expanding subdural hematoma and INR =3); what do you transfuse?
Give PCC
Which blood type does this forward and reverse type result indicate?
Type O-
What does this forward and reverse type result indicate about the type of blood?
This is AB+ blood
What is this patients blood type?
A positive
What are 2 risks when transfusing red cells?
Transfusion reactions 2/2 ABO incompatibility and alloimmunization
Which type of transfusion reaction is of greater risk with plasma transfusion (FFP)?
Allergic rxns
In trauma patient who is hemodynamically unstable (per vitals) what do you transfuse?
1:1 ratio of red cells to plasma
What is the Kell system?
blood ag; ranks 2nd in immunogenicity after D
K = kell
k = cellano
most ppl are kk so alloAbs to K are common –> IgG rxn at 37C = HDN and hemolytic transfusion rxn
“kell kills”
What is the Kidd system?
“treacherous kidds”
Jka or Jkb
Abs against both phenotypes seen commonly - low titer and dissappear rapidly
Get a delayed hemolytic transfusion rxn (IgG)
(will have no ab detected during screen, but then reappears upon transfusion w/ Kidd + unit)
What is the Duffy system?
“duffy lives”
Fya or Fy b
caucasians usually eather a, b, or ab
AAs usually a-b- –> resistant to plasmodium vivax
IgG assoc w/ HDN and hemolytic transfusion rxn
What is the lewis system?
“lewis lives”
IgM warm abs, naturally occuring
found in secretions and plasm –> then absorbed onto RBC membrane
have to be a secretor and Hh gene to have Ag
