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Dispensing Exam Three > Transdermal > Flashcards

Transdermal Flashcards

0
Q

Does the nitroglycerin transdermal system relieve acute attacks?

A

No, nitroglycerin transdermal systems are only indicated for prevention of angina pectoris.

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1
Q

The drug is evenly distributed, can be cut in half, contains a release liner, and is released from the adhesive in which transdermal system

A

Adhesive matrix

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2
Q

What’s the trade name for ranolazine?

A

Ranexa

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3
Q

What type of matrix are contained in Minitran and Nitro-Dur?

A

Adhesive matrix

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4
Q

How often is Minitran given?

A

Qday

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5
Q

Which transdermal system can’t be cut in half and haas rate controlling membrane?

A

Reservoir

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6
Q

How often should ranolazine (Ranexa) be given?

A

Bid

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7
Q

How often should Nitro-Dur and Minitran be given?

A

Wear for 12 hours then take off for 12 hours

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8
Q

What’s the term for painful intercourse?

A

Dyspareunia

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9
Q

What’s the term for inflammation of the vagina of thinning and shrinking of tissues?

A

Atrophic vaginitis

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10
Q

What’s the BBW for estradiol transdermal systems such as Menostar, Climara, Vivelle-Dot, Alora, and Minivelle?

A

Increased risk of CVD, dementia, and endometrial cancers

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11
Q

Which estradiol transdermal patch is indicated for osteoporosis only?

A

Menostar

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12
Q

Which type of matrix are the estradiol transdermal systems?

A

Adhesive

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13
Q

Which are the strengths for Minivelle?

A

0.0375, 0.05, 0.075, 0.1 mg/24 hours

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14
Q

Which estradiol transdermal comes in a strength of 0.014 mg/24 hours

A

Menostar

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15
Q

How often is Climara given?

A

Qweek

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16
Q

How often are Vivelle Dot and Alora given?

A

Twice weekly

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17
Q

How often is Menostar given?

A

Qweekly 0.014 mg/24 hours

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18
Q

What are the indications for estradiol transdermal systems?

A
  1. Vasomotor symptoms
  2. Vaginal atrophy
  3. Osteoporosis
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19
Q

How often are Minivelle, Alora, and Vivelle-Dot given?

A

Twice weekly

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20
Q

Which estradiol topical emulsion contains soybean oil?

A

Estrasorb

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21
Q

How often is Estrasorb (estradiol) given?

A

2 packets every morning 0.05 mg/2 packets; place one packet on the leg for 3 minutes, one packet on right leg for 3 minutes, rub the excess on the buttocks

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22
Q

What’s the trade for estradiol 0.021 mg/spray transdermal spray?

A

Evamist

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23
Q

Where do you spray Evamist?

A

Spray on the inside of the arm

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24
Q

How often should Evamist be given?

A

One spray daily

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25
Q

Which estradiol products are indicated for vasomotor symptoms only?

A
  1. Estrasorb-left and right leg then buttocks
  2. Evamist-forearm
  3. Divigel-upper thigh
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26
Q

How often is Divigel given?

A

Daily

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27
Q

What’s the trade for ethinyl estradiol + norelgestromin?

A

Ortho Evra-given weekly-adhesive matrix-apply 1 patch for 3 weeks then go patch free for one week repeat

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28
Q

How often is Activella given?

A

Qday

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29
Q

What are the trade names for estradiol + norethindrone?

A

CombiPatch, Activella

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30
Q

What’s the trade name for estradiol and levonorgestrel?

A

Climara Pro

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31
Q

What’s the trade for the conjugated equine estrogens?

A

Premarin Vaginal Creams

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32
Q

What’s the trade for the 10 mcg vaginal tablet?

A

Vagifem

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33
Q

What’s the trade for the 0.1 mg/g vaginal cream?

A

Estrace

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34
Q

What’s the maintenance dose for Estrace?

A

1-3x a week

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35
Q

What’s the dosing interval for Femring?

A

0.05 and 0.1 mg/24 hours every three months

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36
Q

Which are indicated for VM, VA, and O?

A

Activella-comes in 0.5 mg/0.1 mg tablet as well as 1 mg/0.5 mg tablet

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37
Q

How often is CombiPatch given?

A

Twice weekly

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38
Q

How often is Activella given?

A

Qday

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39
Q

What’s the trade for the 0.625 mg/g vaginal cream?

A

Premarin Vaginal Cream

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40
Q

What’s the initial dose for Vagifem?

A

1 tablet qday for 2 weeks then a maintenance dose of 1 tablet twice weekly

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41
Q

Which are indicated for VA only?

A

Vagifem, Premarin Vaginal Cream

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42
Q

Which estradiol must be refrigerated?

A

CombiPatch

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43
Q

What are Climara Pro’s indication?

A

Indicated for VM and O

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44
Q

What percent is estradiol topical gel?

A

0.1% in 0.25, 0.5, 1 gram packets of gel

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45
Q

What’s the dosing interval for Estrace?

A

Initial: give daily for 2 weeks then after / weeks give half a dose daily daily for 2 weeks
Maintenance: 1-3x weeks

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46
Q

Which estradiol products contain alcohol USP?

A

Evamist, Divigel

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47
Q

How much testosterone do men produce daily?

A

5 mg/day

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48
Q

What are the synthetic derivatives of testosterone?

A

Anabolic steroids

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49
Q

What drugs do testosterone transdermal systems interact with?

A

They decrease anticoagulant and insulin requirements

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50
Q

What control level are anabolic steroids?

A

CIII

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51
Q

How often should testosterone transdermals be given?

A

All are given daily-Androderm, AndroGel, Testim, Fortesta, Axiron

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52
Q

What testosterone transdermal patch comes in strengths of 2 mg/24 hours and 4 mg/24 hours?

A

Androderm

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53
Q

Which testosterone transdermal is a reservoir patch?

A

Androderm

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54
Q

Which testosterone transdermal comes in 5 gram single dose packets? 50 mg testosterone= 5 mg absorbed

A

Testim

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55
Q

What single dose packet sizes does AndroGel come in?

A

2.5 grams, 5 gram= 25 mg, 50 mg testosterone-2.5 mg, 5 mg absorbed via the shoulder

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56
Q

What % metered dose pump does AndroGel come in?

A

1%, 1.62%

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57
Q

With a 1% AndroGel testosterone pump, how many milligrams are absorbed via the shoulder?

A

5 mg absorbed via the shoulder; 1 pump=12.5 mg x 4 pumps= 50 mg with 5 mg absorbed

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58
Q

What’s the metered dose pump that includes alcohol USP used as a topical solution?

A

Axiron-give daily-ALL testosterone transdermals are DAILY

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59
Q

Which testosterone metered dose pump is applied as two pumps to each thigh to minimize secondary exposure?

A

Fortesta

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60
Q

How often is Kapvay given?

A

Bid (maintenance)

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61
Q

What is. Kapvay indicated for?

A

ADHD

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62
Q

How often is Catapres given?

A

Qweek it comes in 0.1, 0.2, 0.3 mg/24 hours

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63
Q

What is Catapres indicated for?

A

Hypertension

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64
Q

What strengths does Kapvay come in?

A

0.1 mg, 0.2 mg ER tablet

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65
Q

What’s the precaution with fentanyl transdermal system?

A

All may be fatal to children so discard appropriately

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66
Q

How often is Duragesic given?

A

q72h

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67
Q

Which fentanyl transdermal is given for chronic pain?

A

Duragesic-note 12 hour onset

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68
Q

What strengths does fentanyl come in?

A

12.5, 25, 50, 75, 100 mcg/hr

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69
Q

How often is Actiq given?

A

q4h-Rub on side of cheek for 15 minutes

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70
Q

What’s the trade for the transmucosal lozenge on a stick

A

Actiq

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71
Q

How often is Onsolis given?

A

q2h

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72
Q

How often is the sublingual fentanyl tablet given?

A

Abstral

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73
Q

What’s the trade for the fentanyl nasal spray?

A

Lazanda-1 spray in 1 nostril

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74
Q

Which fentanyl product should be placed in a child resistant container?

A

Lazanda

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75
Q

What’s the trade for the fentanyl but cal tablet?

A

Fentora

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76
Q

What’s the trade for the fentanyl sublingual tablet?

A

Abstral given q2h

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77
Q

How long can a scopolamine patch be left on?

A

3 days-note: place behind ear for 4 hours

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78
Q

If a scopolamine patch is used for surgery, when should it be placed behind the ear?

A

The evening before surgery

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79
Q

What strength does scopolamine come in?

A

5 mcg/hr

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80
Q

What’s the trade for scopolamine patch?

A

Transderm-Scop

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81
Q

Which transdermal patch is indicated for pain associated with post herpetic neuropathy?

A

Lidoderm-lidocaine

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82
Q

What’s the trade for the 5 % lidocaine transdermal patch?

A

Lidoderm

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83
Q

How often and how long should Lidoderm be applied?

A

Apply up to 3 patches a day at the same time; put one on for 12 hours, then remove for 12 hours

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84
Q

What’s the trade for zoster vaccine?

A

Zostavax

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85
Q

What’s the trade for varicella vaccine?

A

Varivax

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86
Q

What are the indications for Neurontin?

A
  1. PHN

2. Partial seizures

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87
Q

What are the indications for Lyrica?

A
  1. PHN
  2. Partial seizures
  3. DPN
  4. Fibromyalgia
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88
Q

What’s the trade for mirabegron?

A

Myrbetriq

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89
Q

What’s the trade for fesoteridone?

A

Toviaz

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90
Q

What’s the trade for solifenacin?

A

Vesicant

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91
Q

What’s the trade for darifenacin?

A

Enablex

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92
Q

What’s the trade for the ER trospium capsule?

A

Sanctura XR

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93
Q

What’s the trade for the IR trospium tablet?

A

Sanctura

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94
Q

How should trospium be taken?

A

Take on an empty stomach

95
Q

What’s the 10% topical oxybutynin gel?

A

Gelnique

96
Q

What’s the trade for the IR oxybutynin tablet?

A

Ditropan

97
Q

What’s the trade for the ER oxybutynin tablet?

A

Ditropan XL

98
Q

What’s the trade for the oxybutynin transdermal 3.9 mg/24 hours adhesive?

A

Oxytrol

99
Q

How often should Oxytrol be given?

A

Twice weekly

100
Q

Which class is Myrbetriq a part of?

A

Beta 3 agonist

101
Q

Where is Gelnique applied?

A

The abdomen

102
Q

How often is Gelnique given?

A

Qday

103
Q

How often should Daytrana be given?

A

Qday

104
Q

What’s the indication for methylphenidate and what class?

A

ADHD; Controlled II

105
Q

What strength does Daytrana come in?

A

10, 15, 20, 30 mg/9 hours

106
Q

Where do you apply Daytrana and for how long?

A

Wear on the hip for 2 hours before needed, then take off 9 hours later.

107
Q

What’s the trade for granisetron?

A

Sancuso

108
Q

How often should Sancuso be given?

A

Qweek-3.1 mg/24 hours

109
Q

What are Zelapar and Eldepryl indicated for?

A

AntiParkinson’s agent

110
Q

What’s the generic for Emsam, Eldepryl, and Zelapar?

A

Selegiline

111
Q

What’s the trade for ODT selegiline?

A

Zelapar

112
Q

What’s the indication for Emsam?

A

MAOI depressant

113
Q

What’s a drug interaction with Emsam?

A

Tyramine 9 mg, 12 mg; avoid pseudoephedrine and phenylephrine

114
Q

What strengths does Emsam come in?

A

6, 9, 12 mg/24 hours

115
Q

How often should Sancuso be given?

A

Qweek

116
Q

How often should Emsam given?

A

Qday

117
Q

What’s the trade for aprepitant?

A

Emend

118
Q

What’s the trade for ondansetron?

A

Zofran

119
Q

What’s the trade for dolasetron?

A

Anzemet

120
Q

What’s the trade for palonosetron?

A

Aloxi

121
Q

Which antiemetic is indicated for N/V patients receiving chemotherapy for 5 straight days?

A

Sancuso-granisetron

122
Q

How soon should Sancuso be applied to upper arm before treatment?

A

24 hours and also taken off 24 hours after last treatment

123
Q

What’s the trade for galantamine?

A

Razadyne

124
Q

What’s the trade for donepezil?

A

Aricept

125
Q

What’s the trade for Exelon?

A

rivastigmine?

126
Q

Where should Exelon Patch be applied?

A

In the middle of the back

127
Q

How often should Exelon Patch be applied?

A

Qday; it comes in strengths of 4.6,9.5/24 hours

128
Q

What’s the dosing interval for Exelon Patch?

A

4.6 mg x 1 month, then increase to 9.5 mg as maintenance dose

129
Q

How often should Butrans be given?

A

Weekly

130
Q

What’s the trade for parenteral buprenorphine?

A

Buprenex

131
Q

What’s the sublingual buprenorphine tablet?

A

buprenorphine

132
Q

What’s the indication for Buprenex?

A

Addiction

133
Q

What’s the trade for diclofenac epolamine?

A

Flector Patch

134
Q

How often should Flector Patch be given?

A

Bid

135
Q

Which COX enzyme does Flector Patch inhibit?

A

COX-2

136
Q

What are the indications for Flector Patch?

A
  1. Strains-stretched muscle

2. Sprains-stretched ligaments

137
Q

What’s a drug interaction with Flector Patch?

A

Aspirin

138
Q

What’s the trade for galantamine?

A

Razadyne

139
Q

How often should Butrans be given?

A

Qweek comes in 5, 10, 20 mcg/hour

140
Q

Which strength of buprenorphine are used in opioid tolerant patients?

A

10 and 20 mcg/hour

141
Q

What’s the dosing interval for Exelon Patch?

A

4.6 mg x 1 month; then increase to 9.5 mg as maintenance dose

142
Q

What category is Zyban?

A

Aminoketone antidepressant

143
Q

What’s the dosing interval for Zyban?

A

Take 1 tablet for 3 days then bid for 12 weeks

144
Q

How often should Zyban be started before trying to quit?

A

Give one week to reach therapeutic levels

145
Q

What’s the dosing interval for Chantix?

A

Take 0.5 mg qday for 3 days, then 0.5 mg bid for 4 days, then 1 mg bid for 12 weeks

146
Q

What’s Chantix mechanism of action?

A

Nicotine receptor agonist; varenicline binds to its receptor and produces nicotine-like effects and inhibits nicotine

147
Q

What’s the DI for Nicoderm CQ?

A

Daily

148
Q

What are the strengths of Nicoderm CQ?

A

7 mg, 14 mg, 21 mg/24 hour adhesive matrix

149
Q

What’s the DI for Nicoderm CQ based off of?

A

Cigarettes smoked per day
>10 cigarettes: 21 mg-6 weeks, 14 mg and 7 mg-2 weeks
<10 cigarettes: 14 mg-6 weeks, 7 mg-2 weeks

150
Q

Where should Nicoderm CQ be applied?

A

Upper part of arm; remove after 24 hours (do not reuse this site for 7 days) and apply new patch to different site-fold patch in half to discard

151
Q

What’s the max daily dose for Nicotrol Inhaler?

A

Max daily dose/day 16 cartridges= 4 mg cartridge; contains enough nicotine for 20 minutes of active puffing; transmucosal so do. to inhale into lungs

152
Q

Trade for cromolyn sodium?

A

Nasalcrom

153
Q

Class for Nasalcrom?

A

Mast Cell Stabilizers

154
Q

Trade for desmopessin acetate?

A

DDAVP, Stimate

155
Q

Which class is DDAVP and Stimate?

A

desmopessin acetate

156
Q

Trade for ipratropium bromide?

A

Atrovent Nasal Spray

157
Q

Which class is Atrovent Nasal spray?

A

Anticholinergics

158
Q

Which class is Astelin, Astepro?

A

Antihistamines

159
Q

Which condition are Miacalcin, Fortical indicated for?

A

calcitonin

160
Q

Which class is Omnaris, Nasonex, Veramyst, Flonase, Rhinocort Aqua, Nasacort AQ?

A

Corticosteroids

161
Q

What’s the trade for triamcinolone?

A

Nasacort AQ

162
Q

Trade for ciclesonide?

A

Alvesco

163
Q

Term for rate of diffusion through the skin?

A

Flux

164
Q

How do you apply a transdermal patch?

A

Place patch in the middle of the palm and press down on area firmly for 10 seconds to get contact with edges

165
Q

How often should Minitran or Nitro-Dur be given?

A

Qday or daily

166
Q

Can you take Minitran or Nitro-Dur for an acute attack?

A

No, it’s for prevention of angina pectoris

167
Q

What’s the rate of Minitran?

A

0.1 mg/hr

168
Q

How long do you wear Minitran?

A

12 hours then give 12 hour break

169
Q

Side effect of Minitran?

A

Headache

170
Q

How often should Ranexa be given?

A

Twice daily; comes in 500 mg, 1000 mg strength

171
Q

What category is Ranexa?

A

Vasodilator

172
Q

Name of the estrogen hormone indicated for hormone replacement therapy in post-menopausal women?

A

Estradiol

173
Q

Which estradiol transdermal system is indicated for osteoporosis only?

A

Menostar

174
Q

What BBW do estradiol transdermals have in pre-menopausal women?

A

Endometrial cancer

175
Q

What BBW do estradiol transdermals have in post-menopausal women?

A

CVD and dementia

176
Q

Strengths of Climara?

A
  1. 025 mg/24 hour
  2. 0375 mg/24 hour
  3. 05 mg/24 hour
  4. 06 mg/24 hour
  5. 075 mg/24 hour
  6. 1 mg/24 hour
177
Q

Strengths of Vivelle-Dot?

A
  1. 025 mg/hr
  2. 0375 mg/hr
  3. 05 mg/hr
  4. 075 mg/hr
  5. 1 mg/24 hour

Basically one less than Climara…there’s no 0.06 mg/hr

178
Q

Strengths for Alora?

A
  1. 025 mg/24 hour
  2. 05 mg/24 hour
  3. 075 mg/24 hour
  4. 1 mg/24 hour
179
Q

Strength of Menostar?

A

0.014 mg/24 hour

180
Q

When is Estrasorb given?

A

In the morning

181
Q

When is Evamist given?

A

Daily or qday

182
Q

What is Estrasorb indicated for?

A

Vasomotor symptoms only

183
Q

Which estradiol should you not use in allergic to peanuts?

A

Estrasorb

184
Q

How often should Evamist be given?

A

Daily

185
Q

What’s the indication for Evamist?

A

Vasomotor symptoms

186
Q

Strength of Evamist?

A

0.021 mg/spray

187
Q

Indications for CombiPatch?

A

VM, VA

188
Q

Dosing interval for CombiPatch?

A

Twice weekly

189
Q

Dosing interval for Climara Pro?

A

Qweek

190
Q

Indication for Climara Pro?

A

VM, O

191
Q

Term for a synthetic progesterone?

A

Progestin

192
Q

CombiPatch should it be kept at room temp or refrigerated?

A

Refrigerated

193
Q

Max pieces of Nicolette DS?

A

20

194
Q

Max pieces of Nicorette?

A

30 pieces

195
Q

Precaution with Nicorette?

A

Do not swallow

196
Q

How is Nicorette absorbed?

A

Buccal mucosa

197
Q

The rate and extent of Nicotine is dependent on?

A

pH dependent

198
Q

What should be avoided when taking Nicorette?

A

Coffee, soft drinks, fruit juices

199
Q

How many times should you chew Nicorette?

A

15 times until peppery taste or tingling subsides then place between cheek and gym until taste is gone….repeat for 30 minutes

200
Q

Which nicotine lozenge strength must be taken within 30 minutes of waking?

A

4 mg

201
Q

Which nicotine lozenge should be taken after 30 minutes of waking?

A

2 mg

202
Q

What’s the dosing interval for nicotine lozenges?

A

Take 1 lozenge either 2 or 4 mg every 1 to 2 hours for 6 weeks then q2-4 hours for 3 weeks then q4-q8 hours every 3 weeks

203
Q

Nicotrol Inhaler contain nicotine for how many minutes of active puffing?

A

20 minutes

204
Q

Nicotine lozenge is dose dependent on?

A

Time to first cigarette

205
Q

What type of system is Nicoderm CQ?

A

Adhesive matrix transdermal system

206
Q

Where should Nicoderm CQ be applied?

A

Apply daily to clean, hairless, dry area on upper outer part of arm

207
Q

Is a person smokes less than 20 cigarettes a day, what’s the DI?

A

14 mg for 6 weeks

7 mg for 2 weeks

208
Q

Is a person smokes more than 20 cigarettes a day, what’s the DI?

A

21 mg for 6 weeks, 14 mg for 2 weeks, 7 mg for 2 weeks

209
Q

Category for Lidoderm?

A

Local anesthetics

210
Q

Does Lidoderm contain percutaneous absorption enhancer?

A

No; don’t want it to go into systemic circulation

211
Q

Lidoderm treats?

A

Pain from PHN, herpes zoster, varicella virus

212
Q

What age group is Zostavax indicated for?

A

Patients 50 and older

213
Q

How often should Oxytrol be taken?

A

Twice weekly comes in 3.9 mg/24 adhesive matrix

214
Q

What’s the TC for Oxytrol?

A

Antispasmodic or Anticholinergic

215
Q

How often should Gelnique be given?

A

Daily

216
Q

How should Sanctura and Sanctura XR be taken?

A

On an empty stomach

217
Q

How often should Emsam be given?

A

Daily

218
Q

What’s the category for Emsam?

A

MAOI antidepressant

219
Q

What’s the trade of the only transdermal patch indicated for depression?

A

Emsam

220
Q

Trade for selegiline capsule?

A

Eldepryl

221
Q

Trade for selegiline ODT?

A

Zelapar

222
Q

What’s the trade for selegiline capsule?

A

Eldepryl

223
Q

What are Eldepryl and Zelapar indicated for?

A

AntiParkinson’s

224
Q

What adhesive matrix strengths does Ensam come in?

A

6 mg/24 hr, 9 mg/24 hr, 12 mg/24 hr

225
Q

What’s the category for Emsam?

A

MAOI antidepressants

226
Q

Patient counseling for Sancuso?

A

Avoid photo toxic reaction by avoiding sun to area patch was applied for 10 days following removal.

227
Q

How often should Exelon Patch be given?

A

Daily

228
Q

What’s the strength for Exelon patch?

A

4.6 mg/24 hr; 9.5 mg/24 hr

229
Q

What’s the category for Exelon patch?

A

Cholinesterase inhibitors

230
Q

How does Exelon Patch work?

A

Increases Acetylcholine levels

231
Q

What dose do patients start on with Exelon patch?

A

4.6 mg initial for a thought then a maintenance of 9.5 mg per dose

232
Q

Where should Exelon Patch be applied?

A

Middle of the back

233
Q

What’s the category for Razadyne and Aricept?

A

Cholinesterase inhibitors

234
Q

What’s the category for Butrans?

A

Opioid analgesics give it weekly do not reuse same site for 3 weeks

235
Q

Trade for buprenorphine adhesive matrix?

A

Butrans in strengths of 5 mcg/hr, 10 mcg/hr, 20 mcg/hr

Dispensing Exam Three (4 decks)

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