Transcription and RNA Processing Flashcards
Gene expression
The process by which information encoded in DNA directs the synthesis of proteins or, in some cases, RNAs that are not translated into proteins and instead function as RNAs
Transcription
The synthesis of RNA using a DNA template
Translation
The synthesis of a polypeptide using the genetic information encoded in an mRNA molecule. There is a change of “language” from nucleotides to amino acids
Exon
A sequence within a primary transcript that remains in the RNA after RNA processing; also refers to the region of DNA from which this sequence was transcribed
Intron
A noncoding, intervening sequence within a primary transcript that is removed from the transcript during RNA processing; also refers to the region of DNA from which this sequence was transcribed
Spliceosome
A large complex made up of proteins and RNA molecules that splices RNA by interacting with the ends of an RNA intron, releasing the intron and joining the two adjacent exons
Template strand
The DNA strand that provides the pattern, or template, for ordering, by complementary base pairing, the sequence of nucleotides in an RNA transcript
Promoter
A specific nucleotide sequence in the DNA of a gene that binds RNA polymerase, positioning it to start transcribing RNA at the appropriate place
RNA polymerase
An enzyme that links ribonucleotides into a growing RNA chain during transcription, based on complementary binding to nucleotides on a DNA template strand
snRNP
Small nuclear ribonucleoproteins recognise splice sites on mRNA. Several different snRNPs join with additional proteins to form a splicesome.
Spliceosome
Interacts with certain sites along an intron, releasing the intron and joining together the two exons that flanked the intron.