(Trans)membrane Transport Flashcards
Membrane Potential
Total charge difference between inside and outside of the cell
Resting (state) potential
Potential when cell is at rest
Transport protein
Integral (almost always multi-subunit) protein
Has dock/binding site at center
When conformation facing outside, molecule enters and binds to inside, inducing conformational change
Ion channels
FASTER
“Pores” that open to allow ions to pass through - usually open only in response to a signal e.g. hormone of voltage change
“Other” (non-ion) transport proteins
SLOWER
Specialized carriers that provide a pathway for larger, polar molecules - generally junction all the time
Uniport
One molecule active transport
Symport
Two or more molecules going in same direction (active transport)
Antiport
At least two molecules going in opposite directions (active transport)
Direct active transport
Aka PRIMARY
Uses energy from ATP hydrolysis
Indirect active transport
Aka SECONDARY
Energy from diffusion of another molecule down its concentration gradient
Na+/K+ ATPase (active transporter)
Antiport: 3 Na+ out of the cell for every 2 K+ into the cell
Direct active transport: Energy from ATP hydrolysis
Na+/glucose Symporter (active transport)
Symport: Na+ and glucose into the cell
Indirect active transport: energy from diffusion on Na+ down its concentration gradient used to transport glucose up its concentration gradient