Tranexamic Acid

Question 1

how does it come

Answer 1

1g in 10mls

Question 2

contras

Answer 2

1. hypersensitivity
2. injury time >3 hours

Question 3

indications

Answer 3

1. significant trauma (<3hrs) with signs of hypovolaemic shock
2. significant active haemorrhaging requiring tourniquet or haemostatic dressings
3. suspected head injury (<3hrs) with GCS motor 4 or below
4. severe PPH >1000ml with hypovolaemia and birth <3hrs

Question 4

route

Answer 4

IV

Question 5

dose

Answer 5

1. 1g slowly over 10/60

OR

2. 1g in 250ml NaCl, slow IV/IO infusion over 10/60

Question 6

Initial volume of dose

Answer 6

10mls or 250ml

Question 7

repeat dose

Answer 7

single dose