Trali

Question 1

1) Transfusion related acute lung injury (TRALI) develops within ___ hours of the transfusion.

Answer 1

6

Question 2

2) On admission as compared to the control group in the study the patients that developed TRALI had all of the following except:

Answer 2

b. Higher admission platelet count

Question 3

3) Patients who developed TRALI had:

Answer 3

d. Longer duration of surgery and longer duration of CPB

Question 4

4) Based on the model from the paper a cut off CPB time of ___ minutes had a 90% sensitivity and 90% specificity in prediction of possible TRALI.

Answer 4

178 min

Question 5

5) Five of the 8 independent variables initially assessed for testing showed significant results. List 3 of these 5. (one point each)

Answer 5

• Total number of transfused blood units
• Duration of CPB
• Duration of surgery

Question 6

6) There were five main findings in this study, list 2 of these findings. (1 point each)

Answer 6

• The incidence of possible TRALI was relatively high
• Patient related risk factors included higher ASA scores, respiratory comorbidity, lower admission hemoglobin, platelet count, and prothrombin time.

Question 7

True or false: The study showed the PaO2/FiO2 ratio was more sensitive than Sao2 pulse oximetry measurement for diagnosis of ALI (as a prerequisite for diagnosis of possible TRALI).

Answer 7

True