Trace Minerals Flashcards

0
Q

what is the best source of Zinc

A

oysters

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1
Q

what are the trace minerals

A
Molybdenum
chromium
copper
zinc
iron
fluoride
selenium
manganese
Iodine
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2
Q

what is a symptom of zinc toxicity

A

Metallic taste

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3
Q

what results from a zinc defficency

A

dermatitis
decreased immunity
decreased taste

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4
Q

what form of zinc has decreased absorption

A

supplements

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5
Q

what is the function of zinc

A

Folate digestion via conjugase enzyme
superoxide dismutase
a cofactor for 300+ enzymes

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6
Q

what will decrease absorption of zinc

A

folic acid

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7
Q

what are the functions of copper

A

collagen cross-linking
superoxide dismutase
ATP generation

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8
Q

what pathology results from a copper toxicity and what is the a classic symptom

A

Wilson’s disease , classic symptom is kayser-fleischer rings ( copper in the cornea)

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9
Q

what genetic pathology results in a copper deficiency due to an increase in copper excretion and decrease in copper absorption

A

Menkes syndrom

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10
Q

what is a symtom of copper deficiency

A

skin depigmentation

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11
Q

what is the function of chromium

A

insulin secretion

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12
Q

what does a chromium deficiency result in

A

insulin resistance

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13
Q

what is the function of iodine

A

part of T4 and T3

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14
Q

what does a iodine deficiency result in

A

Goiter

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15
Q

what does and Iodine toxicity result in

A

burning mouth

hypothyroidism

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16
Q

what is the functions of molybdenum

A

functions as a co-factor for S metabolism and uric acid synthesis

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17
Q

what results from a Molybdenum toxicity

A

gout

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18
Q

what is the best source of molybdenum

A

plants

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19
Q

what is the function of manganese

A

Superoxide dismutase in mitochondria

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20
Q

what is the source of manganese

A

plants

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21
Q

what results from a toxicity of manganese

A

Tremors

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22
Q

what is the function of selenium

A

cofactor for glutathione peroxidase and T4 to T3

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23
Q

what is a symptom of selenosis

A

Brittle nails

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24
Q

what is the best source of selenium

A

Brazil nuts

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25
Q

what pathologies result from a Selenium deficiency

A

Keshan’s Disease (heart disease in kids)

Kashin-Beck’s disease (osteoarthritis)

26
Q

what trace mineral is highly dependent upon soil content

A

selenium

27
Q

what country is selenium deficiency prevalent in

A

China

28
Q

what is the function of Fluoride

A

decrease cavities

strengthen bones

29
Q

what is the source of fluoride

A

fluorinated water

toothpaste

30
Q

what is a toxicity of fluoride called

A

fluorosis

31
Q

what occurs with fluorosis

A

bone pitting

teeth mottling

32
Q

what occurs with a deficiency of fluoride

A

cavities

osteoporosis

33
Q

what is the number 1 nutritional deficiency in the United States

A

Iron

34
Q

what are the two types of iron

A

Nonheme

Heme

35
Q

what is iron transported out of the enterocyte by

A

ferroportin

36
Q

what other trace mineral in needed for ferroportin to work

A

Copper

37
Q

what is iron transported as in the blood

A

transferrin

38
Q

what is the storage protein of iron

A

ferritin

39
Q

where is ferritin found

A

spleen
liver
bone morrow
enterocyte

40
Q

what three locations of ferritin are know as iron stores

A

spleen
liver
bone marrow

41
Q

what results from an iron toxicity

A

hemochromatosis

42
Q

what does hemochromatosis lead to

A

organ damage

43
Q

what are symptoms of iron deficiency

A

fatigue
pallor
decreased immunity

44
Q

what may result due to iron deficiency

A

microcytic hypochromic anemia

45
Q

who is at risk for iron deficiency

A
6mo- 2yr olds
10-19 yr old males
male runners
10-44 yr old females
all female athletes
46
Q

what is the function of heme iron

A

O2 transport

cytochromes

47
Q

is heme or non heme iron absorbed more

A

Heme iron

48
Q

what are the sources of heme iron

A

Beef

Fish

49
Q

how is heme iron absorbed

A

facilitated diffusion via HCP1

50
Q

what are sources of nonheme iron

A

plants and supplements

51
Q

what is non heme iron digested by

A

ferrireductase (requires Vit C)

52
Q

how is non heme iron absorbed

A

facilitated diffusion using divalent mineral transport (DMT)

53
Q

do nonheme supplements have an increased or decreased absorption rate

A

decreased

54
Q

how much of a trace mineral do we need

A

<100mg/day

55
Q

what enzyme does zinc need in order to do collagen cross linking

A

lysyl oxidase

56
Q

what mineral is considered an antioxidant

A

selenium

57
Q

what does the 3 mean in “T3”

A

it has 3 iodines

58
Q

what does the 4 mean in “T4”

A

it has 4 iodines

59
Q

what is mottling of teeth

A

discoloration

60
Q

what can cause tetany

A

low vit D, Ca, Mg, K,

High Phosphorus, Na, Fe, Zn, Copper

61
Q

what enzyme does zinc need in order to do collagen cross linking

A

lysyl oxidase

62
Q

what mineral is considered an antioxidant

A

selenium

63
Q

what removes iron from HCP1

A

Heme oxygenase