Trace Minerals Flashcards

1
Q

What are the two types of trace elements?

A

Metals (e.g., Selenium)
Halogens (e.g., Fluoride, Iodine)

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2
Q

What essential roles do trace elements play in the body?

A

Maintain health and tissue functions
Perform unique metabolic roles

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3
Q

What is the typical concentration of trace elements in the body?

A

Wet tissue: Less than 1 µg/g
Dry body weight: Less than 0.01%

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4
Q

What trace element enhances insulin action and supports glucose and lipid metabolism?

A

Chromium

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5
Q

What conditions can result from chromium deficiency?

A

Insulin resistance
Impaired glucose tolerance (Type II Diabetes Mellitus)
Hyperlipidemia

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6
Q

What are the toxic effects of chromium?

A

Skin ulcers
Renal and hepatic necrosis

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7
Q

What trace element supports hemoglobin synthesis and is a component of vitamin B12?

A

Cobalt

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8
Q

What conditions can result from cobalt deficiency?

A

Anemia
Growth depression

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9
Q

What toxic effects are associated with cobalt?

A

Heart failure
Hypothyroidism

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10
Q

What trace element is essential for cellular respiration and collagen synthesis?

A

Copper

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11
Q

What disease is caused by copper deficiency?

A

Menkes disease

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12
Q

What effect does excess copper have on nutrient absorption?

A

Interferes with iron and zinc absorption

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13
Q

What condition is characterized by sparse, kinky hair, failure to thrive, and nervous system deterioration?

A

Menkes disease

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14
Q

What genetic mutation causes Menkes disease?

A

ATP7A gene mutation, which disrupts copper transport

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15
Q

How is Menkes disease diagnosed?

A

Brittle, sparse, tangled hair
Low serum copper and ceruloplasmin levels

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16
Q

What trace element reduces pain, protects against gum disease, and prevents tooth decay?

17
Q

What is the primary function of fluoride?

A

Prevention of dental caries

18
Q

What condition results from fluoride deficiency?

A

Dental caries

19
Q

What trace element is essential for thyroid hormone synthesis (T3, T4)?

20
Q

What conditions can result from iodine deficiency?

A

Goiter
Cretinism
Myxedema

21
Q

What condition results from excessive iodine intake?

A

Thyrotoxicosis

22
Q

What trace element is essential for oxygen transport and is a key component of hemoglobin?

23
Q

What condition results from iron deficiency?

A

Iron deficiency anemia

24
Q

What condition results from excessive iron accumulation?

A

Hemochromatosis

25
What trace element plays a role in bone formation and connective tissue maintenance?
Manganese
26
What condition results from manganese deficiency?
Skeletal defects
27
What conditions are linked to manganese toxicity?
Parkinson’s disease Psychiatric disorders
28
What trace element supports DNA metabolism?
Molybdenum
29
What conditions result from molybdenum deficiency?
Growth depression Cretinism Goiter
30
What toxic effects are associated with molybdenum?
Anemia Thyrotoxicosis
31
What trace element helps prevent oxidative lipid damage?
Selenium
32
What disease is caused by selenium deficiency?
Keshan disease
33
What are the toxic effects of selenium?
Hair and nail loss Liver failure
34
What trace element is essential for protein synthesis?
Zinc
35
What conditions are associated with zinc deficiency?
Acrodermatitis enteropathica Growth retardation Immunodeficiency Infertility Delayed wound healing Osteoporosis
36
What condition results from excessive zinc intake?
Gastrointestinal irritation