TQ's test 2 Flashcards
HBIG what type of immunzation
immune globulin, passive immunity
the reactivity of the host
immunologic competency
which immunoglobin crosses the placenta
IgG
How to immunize for diptheria adults verse children
chidren get 16 units, adults 2 units
how often do people need a tetanus immunzation
every ten years to boost immunity
tdap is for who
old children and adults
what is the most common cause of genital warts
6 and 11 hpv
is the flu vaccine the same every year
no it varies every year
what must you be careful about with the caricella vaccine
you must acoid salicylates (asprin) for the next 6 weeks
primary focus of dylipidemia treatment
LDL
Name a bile acid sequestrant
cholestyramine
contraindication to cholestyramine
if high triglycerides over 400 mg/dl
niacin is known for this effect
best at lowering LDL as it lowers it by 25%
Side effects of niacin
flushing as caused by histamine
MOA HMG CoA Reductase Inhibitors (Statins)
increases LDL CATABOLISM
What must you do if you have muscle pain on statins
must check CPK
Avoid Atorvastain in
those with active liver disease
Must check what before taking atorvastatin
liver status (cant prescribe if liver has active liver disease)
What is an increased risk of Gemfibrozil
gallstone formation due to increased cholesterol concentration in the bile
MOA of Ezetimibe
inhibits absorption of cholesterol at brush border of the small intestine via the sterol transporter NPC1L1
Avoid omega 3 acid ethyl esters if
patient has shellfish allergy
if you have a shellfish allergy avoid
lovaza!
Lovaza avoid if pt has
shellfish allergy
Drugs capable of inducing hyperuricemia and gout
diuretics, l-dopa, pyrazinaminde, ethabutol, nicotinic acid, vitamin B12, cyclosporine, salcylates if you have less than 2gm per day, ethanol
T/F in the treatment of gout it is important to treat all types of hyperuricemia
false hyperuricemia in of its self does not require any treatment other than diet
Which Nsaid is not a uricosuric agent
OXAPROZIN
isolated from autumn crocus
Colchicine
colchicine adr
burning throat pain, bloody diarrhea
When should therapy for probenecid and sulfinpyrazone be started after an acute attack? why?
2-3 wks later, due to increased risk of of uric stones
what is more likely to cause a rash probenecid or sulfinpyrazone
probenecid more likely to cause allergic dermatitis
indication for alopurinol
chronic tophaceous gout
MOA of urate oxidase compounds
oxidizes urate —> allantoin (which allows it to be urinated)
pegloticase use
severe refractory gout only
standard for prophylaxis of gout is
allopurinol
which med’s (2 of em) may increase risk for gout?
cyclosporine, diuretics
avoid what if diagnoised with gout recently
etoh
MOST effect on LESP
calcium carbonate
which h2-receptor antagoinst is used for wart treatment
CIMETIDINE as it has immunomodulatory effects
lansoprazole is a
protton pump inhibitor
adr of metoclopramide
extra-pyramidal symptoms
cannabinoids use
refractory chemo-related emesis
purge by excess volume
iso-osmotic electrolyte colonic lavage solutions
mineral oil is a? does what
fecal softener, that will prevent your absorption of fat souble vitamins
a prodrug converted to 6-MP
AZA–azathioprine
rescue drug for methotrexate
leucovorin
for symptomatic relief of non-infectious diarrhea in adult patients with HIV/AIDS on anti-retroviral therapy
crofelemer
probiotic problems
unknown whethere organisms living or not, infection in susceptible indivuals, manufacture is not regulated
goal of treating asthma
prevent chronic and troublesome symptoms
COPD is it reversible
irreversible
primary cause of COPD
cigarette smoking
combivent is made of? what is it for?
albuterol, ipratropium and its for brochodilation
short-acting beta-2 agonists example
albuterol
inhaled corticosteriods place in therapy
first-line for chronic symptoms control and preventing the progression of asthma
are leukotriene receptor blockers used for copd
NOOO
cromolyn is a
mast cell stabilizers
omalizumab use
treatment of moderate to severe allergic asthmawith elevated IgE
selective phosphodiesterase type 4 inhibitor
Rofluilast
what can never be a herbal remedie
tobacco
how do herbs differ from conventional drugs
they are often far more dilute
DSHEA
dietary supplement health and education act
All herbs must say
this product has been evaluated by the FDA and is not intended to diagnose, treat or prevent any diease
For a herb to get USP certification it must be
pure and meet limits for contaiminats as well as contain stated ingredients
Safety issues of herbs
unkonwn consequences of long term therapy
MOA of Echinacea
immunostimulant if used short term
zinc moa
will shorten length of common cold as it interrupts viral replication and cell attachment mechanisms
don’t use st john’s wort if
your on other antidepressants it can cause serotonin syndrome
can we use ephedra
no it was removed from market due to cardiac risk
ginger use it for
motion sickness and seasickness
issues with herbs
heavy metals detected, with interact with many drug classes, and contamination of products by containing mircobes mold pestixies
