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Pharmacology > TQ's test 2 > Flashcards

TQ's test 2 Flashcards

1
Q

HBIG what type of immunzation

A

immune globulin, passive immunity

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2
Q

the reactivity of the host

A

immunologic competency

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3
Q

which immunoglobin crosses the placenta

A

IgG

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4
Q

How to immunize for diptheria adults verse children

A

chidren get 16 units, adults 2 units

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5
Q

how often do people need a tetanus immunzation

A

every ten years to boost immunity

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6
Q

tdap is for who

A

old children and adults

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7
Q

what is the most common cause of genital warts

A

6 and 11 hpv

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8
Q

is the flu vaccine the same every year

A

no it varies every year

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9
Q

what must you be careful about with the caricella vaccine

A

you must acoid salicylates (asprin) for the next 6 weeks

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10
Q

primary focus of dylipidemia treatment

A

LDL

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11
Q

Name a bile acid sequestrant

A

cholestyramine

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12
Q

contraindication to cholestyramine

A

if high triglycerides over 400 mg/dl

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13
Q

niacin is known for this effect

A

best at lowering LDL as it lowers it by 25%

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14
Q

Side effects of niacin

A

flushing as caused by histamine

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15
Q

MOA HMG CoA Reductase Inhibitors (Statins)

A

increases LDL CATABOLISM

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16
Q

What must you do if you have muscle pain on statins

A

must check CPK

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17
Q

Avoid Atorvastain in

A

those with active liver disease

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18
Q

Must check what before taking atorvastatin

A

liver status (cant prescribe if liver has active liver disease)

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19
Q

What is an increased risk of Gemfibrozil

A

gallstone formation due to increased cholesterol concentration in the bile

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20
Q

MOA of Ezetimibe

A

inhibits absorption of cholesterol at brush border of the small intestine via the sterol transporter NPC1L1

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21
Q

Avoid omega 3 acid ethyl esters if

A

patient has shellfish allergy

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22
Q

if you have a shellfish allergy avoid

A

lovaza!

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23
Q

Lovaza avoid if pt has

A

shellfish allergy

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24
Q

Drugs capable of inducing hyperuricemia and gout

A

diuretics, l-dopa, pyrazinaminde, ethabutol, nicotinic acid, vitamin B12, cyclosporine, salcylates if you have less than 2gm per day, ethanol

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25
Q

T/F in the treatment of gout it is important to treat all types of hyperuricemia

A

false hyperuricemia in of its self does not require any treatment other than diet

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26
Q

Which Nsaid is not a uricosuric agent

A

OXAPROZIN

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27
Q

isolated from autumn crocus

A

Colchicine

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28
Q

colchicine adr

A

burning throat pain, bloody diarrhea

29
Q

When should therapy for probenecid and sulfinpyrazone be started after an acute attack? why?

A

2-3 wks later, due to increased risk of of uric stones

30
Q

what is more likely to cause a rash probenecid or sulfinpyrazone

A

probenecid more likely to cause allergic dermatitis

31
Q

indication for alopurinol

A

chronic tophaceous gout

32
Q

MOA of urate oxidase compounds

A

oxidizes urate —> allantoin (which allows it to be urinated)

33
Q

pegloticase use

A

severe refractory gout only

34
Q

standard for prophylaxis of gout is

A

allopurinol

35
Q

which med’s (2 of em) may increase risk for gout?

A

cyclosporine, diuretics

36
Q

avoid what if diagnoised with gout recently

A

etoh

37
Q

MOST effect on LESP

A

calcium carbonate

38
Q

which h2-receptor antagoinst is used for wart treatment

A

CIMETIDINE as it has immunomodulatory effects

39
Q

lansoprazole is a

A

protton pump inhibitor

40
Q

adr of metoclopramide

A

extra-pyramidal symptoms

41
Q

cannabinoids use

A

refractory chemo-related emesis

42
Q

purge by excess volume

A

iso-osmotic electrolyte colonic lavage solutions

43
Q

mineral oil is a? does what

A

fecal softener, that will prevent your absorption of fat souble vitamins

44
Q

a prodrug converted to 6-MP

A

AZA–azathioprine

45
Q

rescue drug for methotrexate

A

leucovorin

46
Q

for symptomatic relief of non-infectious diarrhea in adult patients with HIV/AIDS on anti-retroviral therapy

A

crofelemer

47
Q

probiotic problems

A

unknown whethere organisms living or not, infection in susceptible indivuals, manufacture is not regulated

48
Q

goal of treating asthma

A

prevent chronic and troublesome symptoms

49
Q

COPD is it reversible

A

irreversible

50
Q

primary cause of COPD

A

cigarette smoking

51
Q

combivent is made of? what is it for?

A

albuterol, ipratropium and its for brochodilation

52
Q

short-acting beta-2 agonists example

A

albuterol

53
Q

inhaled corticosteriods place in therapy

A

first-line for chronic symptoms control and preventing the progression of asthma

54
Q

are leukotriene receptor blockers used for copd

A

NOOO

55
Q

cromolyn is a

A

mast cell stabilizers

56
Q

omalizumab use

A

treatment of moderate to severe allergic asthmawith elevated IgE

57
Q

selective phosphodiesterase type 4 inhibitor

A

Rofluilast

58
Q

what can never be a herbal remedie

A

tobacco

59
Q

how do herbs differ from conventional drugs

A

they are often far more dilute

60
Q

DSHEA

A

dietary supplement health and education act

61
Q

All herbs must say

A

this product has been evaluated by the FDA and is not intended to diagnose, treat or prevent any diease

62
Q

For a herb to get USP certification it must be

A

pure and meet limits for contaiminats as well as contain stated ingredients

63
Q

Safety issues of herbs

A

unkonwn consequences of long term therapy

64
Q

MOA of Echinacea

A

immunostimulant if used short term

65
Q

zinc moa

A

will shorten length of common cold as it interrupts viral replication and cell attachment mechanisms

66
Q

don’t use st john’s wort if

A

your on other antidepressants it can cause serotonin syndrome

67
Q

can we use ephedra

A

no it was removed from market due to cardiac risk

68
Q

ginger use it for

A

motion sickness and seasickness

69
Q

issues with herbs

A

heavy metals detected, with interact with many drug classes, and contamination of products by containing mircobes mold pestixies

Pharmacology (3 decks)

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