Toxins Flashcards
Toxins
promote damage to the cells or tissues of the hos
exotoxins
toxic proteins that are secreted by living microbes
botulin
Clostridium botulinum neurotoxin causes flaccid paralysis`
tetanospasmin
Clostridium tetani neurotoxin causes simultaneous contraction of opposing muscles, resulting in tetany, which is painful and life-threatening
enterotoxin
scherichia coli, Staphylococcus aureus, Vibrio cholerae and other bacteria produce this toxin, which causes intestinal cells to pump water and salts (electrolytes) from the bloodstream into the intestine, causing diarrhea that leads to dehydration, shock, and even death in the worst cases
diphtheria toxin
in cells of the heart, kidneys and central nervous system by inhibiting protein synthesis
endotoxin
lipopolysaccharide (LPS) portion of the outer membrane of Gram-negative bacterial cell walls which is released when the bacteria disintegrate and causes fever and/or endotoxin shock, depending on its concentration in the bloodstream