Toxin/Antidotes Flashcards

1
Q

acetominophen

A

N-acetylcysteine (replenishes glutathione)

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2
Q

ACHE Inhibitors, organophosphates

A

Atropine > pralidoxime

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3
Q

amphetamines (basic)

A

NH4Cl (acidify urine)

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4
Q

antimuscarinic, anticholinergic agents

A

physostigmine salicylate, control hyperthermia

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5
Q

Benzodiazepines

A

Flumenazil

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6
Q

Beta blockers

A

Glucagon

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7
Q

CO

A

100% O2, hyperbaric O2

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8
Q

Copper

A

penicillamine

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9
Q

arsenic

A

penicillamine

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10
Q

gold

A

penicillamine

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11
Q

digitalis (digoxin)

A

Anti-dig Fab fragments

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12
Q

Heparin

A

protamine sulfate

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13
Q

Iron

A

deferoxamine, deferasirox

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14
Q

Lead

A

EDTA, dimercaprol, succimer, penicillamine

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15
Q

Mercury

A

Dimercaprol (BAL),succimer

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16
Q

arsenic

A

Dimercaprol (BAL),succimer

17
Q

gold

A

Dimercaprol (BAL),succimer

18
Q

Methanol

A

fomepizole >ethanol, dialysis

19
Q

ethylene glycol (antifreeze)

A

fomepizole >ethanol, dialysis

20
Q

methemoglobin

A

methylene blue, vitamin C

21
Q

opioids

A

naloxone, naltrexone

22
Q

salicylates

A

NaHCO3 (alkalinize urine), dialysis

23
Q

TCAs

A

NaHCO3 (plasma alkalinization)

24
Q

tPA

A

aminocaproic acid

25
Q

urokinase

A

aminocaproic acid

26
Q

streptokinase

A

aminocaproic acid

27
Q

warfarin

A

vitamin K (delayed effect), fresh frozen plasma (immediate)