Oncogenes Flashcards
1
Q
BCR-ABL gene product
A
tyrosine kinase
2
Q
BCR-ABL assd tumor
A
CML, ALL
3
Q
BCL-2 gene product
A
antiapoptotic molecule (inhibits apoptosis)
4
Q
BCL-2 assd tumor
A
follicular and undifferentiated lymphomas
5
Q
BRAF gene product
A
serine/threonine kinase
6
Q
BRAF assd tumor
A
melanoma, non-Hodgkin lymphoma
7
Q
ckit gene product
A
cytokine receptor
8
Q
c-kit assd tumor
A
gastrointestinal stromal tumor (GIST)
9
Q
c-myc assd tumor
A
Burkitt lymphoma
10
Q
c-myc gene product
A
transcription factor
11
Q
HER2/neu (c-erbB2) assd tumor
A
breast, ovarian, and gastric carcinomas
12
Q
HER2/neu (c-erbB2) assd gene product
A
tyrosine kinase
13
Q
L-myc assd tumor
A
Lung Tumor
14
Q
L-myc gene product
A
transcription factor
15
Q
N-myc associated tumor
A
Neuroblastoma
