Toxidromes

Question 1

Anticholinergic toxicity s/s

Answer 1

HR/BP increased
RR same
Temp increased
Agitated, delirium, hallucinations
Large, sluggish pupils
Dry, flushed skin
Urinary retention

Question 2

Cholinergic
(organophosphates) toxicity s/s

Answer 2

HR/BP decreased
RR increased
Unchanged temp
Lethargy, seizure, coma, weakness
Small pupils
Diaphoretic
Diarrhea, emesis, salivation

Question 3

Opiates toxicity s/s

Answer 3

decreased HR/BP, RR, temp
Euphoria, somnolence, coma
pinpoint pupils

Question 4

Sedative/hypnotic toxicity s/s

Answer 4

decreased HR/BP, RR, temp
Confused, somnolent, coma

Question 5

Sympathomimetic toxicity s/s

Answer 5

increased H/BP
same RR
Increased temp
agitation, paranoia, hyperactivity
Large, reactive pupils
Diaphoretic

Question 6

Dextromethorphan toxicity s/s

Answer 6

induce a dissociative state and may produce serotonin syndrome–like symptoms

Question 7

Loperamide toxicity s/s

Answer 7

induces an opioid-like high. Symptoms may include a depressed or euphoric state, bradycardia, hypotension, and pinpoint pupils
long-term abuse= cardiac effects

Question 8

serotonin toxicity vs anticholinergic

Answer 8

diaphoretic rather than anhidrotic, hyperreflexive rather than hyporeflexive, and have hyperactive bowel sounds and diarrhea rather than hypoactive bowel sounds and constipation

Question 9

anticholinergic antidote

Answer 9

physostigmine

Question 10

Anticholinesterases antidote

Answer 10

Atropine

Question 11

Organophosphates antidote

Answer 11

Atropine or pralidoxime chloride

Question 12

Benzos antidote

Answer 12

Flumazenil

Question 13

B-Blocker antidote

Answer 13

Glucagon

Question 14

Calcium channel blockers antidote

Answer 14

Calcium

Question 15

Cyanide antidote

Answer 15

Amyl nitrite

Question 16

Iron antidote

Answer 16

Iron

Question 17

Methanol/ethylene glycol antidote

Answer 17

Fomepizole

Question 18

Tricyclic antidepressants antidote

Answer 18

Sodium bicarbonate

Question 19

Warfarin antidote

Answer 19

Vitamin K