Toxidromes Flashcards

1
Q

What is the general approach toxicology

A
Resuscitation 
Risk assessment
Supportive 
Investigations
Decontamination 
Enhance elimination 
Antidote
Disposition
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2
Q

Lithium toxicity clinical presentation

A

GIT - nausea, vomiting, diarrhoea
CNS - tremor, hyperreflexia, ataxia
CVS (rare) - QT prolongation, arrhythmias

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3
Q

Investigations for lithium toxicity

A

ECG
6 hourly lithium levels
UEC
Serum sodium

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4
Q

Decontamination and enhanced elimination for lithium toxicity

A

Whole bowel irrigation within 4 hours if > 50g ingested (requires intubation)
Dialysis (rarely needed) - coma/seizures, serum lithium >4 + renal impairment, serum lithium >5

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5
Q

Disposition for lithium toxicity

A

If serum lithium falls < 1.5 + asymptomatic –> home

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