Toxicology - Treatments Only Flashcards

1
Q

General Treatment strategy for organophosphate/carbamate poisoning

A
  • Consult Clinicall and DECONTAMINATE
  • Supportive care/ABCs
  • Manage Seizures
    • Midazolam (2-5mg IV/IO, 5-10mg IV)
  • Treat Dysrhythmias
    • Standard care, except increased indication for MgSO4 if QTc is prolonged
    • 2mg IV over 15 minutes
  • Atropine for bradycardia/hypotension and secretions
    • 1-2mg IV/IM initial dose
    • repeat double doses q.5minutes to effect
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2
Q

General Treatment strategy for calcium channel blocker poisoning

A
  • BLS Care
  • Atropine first!
    • 0.6mg IV push to max dose of 0.04mg/kg (3mg in most pts.)
  • CLINICALL PRIOR TO THE FOLLOWING THERAPIES
  • Calcium Chloride
    • 1-2g over 10 minutes
    • Target reversal of bradycardia and hypotension
  • Epinephrine
    • IV infusion or PDP if refractory to CaCl2
  • Pacing not included in CPGs, but may be appropriate
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3
Q

General Treatment strategy for beta blocker poisoning

A
  • BLS care
  • Correct hypoglycemia
    • D10W IV, 10-25g
  • Treat Bradycardia FIRST
    • Atropine (0.6mg IV)
    • Transcutaneous pacing
  • Seizure management
    • Midazolam 2-5mg IV/IO or 5-10mg IM
  • CLINICALL CONSULTATION PRIOR TO FOLLOWING THERAPIES
  • Glucagon
    • 5mg IV push
  • Arhythmia management
  • Epinephrine PDP or IV infusion
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4
Q

General Treatment strategy for TCA OD

A
  • BLS care
  • 12-lead ECG
    • wide WRS >100ms
    • Tall R-wave in aVR
    • deep S-waves in I, aVL
    • Tachycardia
  • CONSULT CLINICALL
  • Sodium Bicarbonate
    • 1meq/kg (2-3meq/kg may be required). Repeat 1/2 doses at 10-15 minute intervals
  • Epinephrine PDP or IV infusion
  • MgSO4 for tachydysrhythmia
    • 2mg IV over 15 minutes
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5
Q

From the standpoint of toxicology, which interventions require clinicall consultation prior to initiation?

A
  • Anything outside of standard care
    • NaHCO3 for TCA
    • High dose atropine/glucagon
  • Epinephrine for management of bradycardia/hypotension in;
    • CCB OD
    • B-blocker OD
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