Palliative Care Flashcards
What is the life expectancy of patients who are beneficiaries of the BC Palliative Care Benefits Program?
up to 6 months
A patient currently takes 2mg hydromorphone q4h PO and had 2 x 0.5mg breakthrough doses yesterday. Describe breakthrough SC morphine dosing for this person today
- TDD = 13mg hydromorphone PO
- Convert to morphine PO
- 65mg morphine PO
- Convert to morphine SC
- 32.5mg morphine SC
- Convert to breakthrough dose (10% of TDD)
- 3.25mg SC
The most common route of drug administration in palliative care settings is:
subcutaneous
What are first and second-line pharmacological treatments for delirium?
- First Line = Benzodiazepines
- Midazolam SC
- 2.5-10mg sc q20 mins to settle
- frail older adults: 1.25-5mg sc q20 mins to settle
- Ativan/lorazepam SL
- 1 mg SL (only if prescribed for patient)
- Midazolam SC
- Second Line = Ketamine SC/IM
- No dosing provided under BCEHS guidelines, consult clinicall
What are the inclusion criteria for the palliative care ASTaR pathway? (4)
- Patient is diagnosed with an advanced life-limiting illness OR;
- Care is currently focused on symptom management rather than curative interventions AND;
- Presenting symptoms are considered related to the patient’s palliative condition AND;
- Patient and family agree to treatment in place
How often should breakthrough doses be given?
- orally = q1h
- SC = q30m
breakthrough dosing does not replace regularly scheduled dosing!
Briefly describe equianalgesic doses of morphine, oxycodone, and hydromorphone. Describe differences between PO and SC dosing
- 2mg hydromorphone = 10mg morphine = 7.5mg oxycodone (1 , 5, 3.75)
- PO dosing is double the SC dosing
Are physical restraints effective in management of hyperactive delirium
No!
Avoid the use of physical restraints as they can increase the risk of delirium
What is the significance of a patient requiring 3 or more breakthrough doses in a 24hr period?
they will require adjustment of their daily dosing
What is the maximum SC dose of morphine which may be given?
20mg
Consult clinicall if this is not an effective dose
What are non-opioid pain medications which may be useful in the palliative care setting?
- Acetaminophen
- 500-1,000 mg PO
- May repeat once after 4 hours
- Entonox (PRN)
- Ketamine
- SC dosing not specified, but likely 0.5mg/kg
True or false, the goal of dyspnea management in palliative settings is correction of hypoxia
FALSE!
By definition, it is a subjective sensation and may or may not be associated with hypoxia
How is the TDD (todal daily dose) calculated for a drug given for pain management?
The total daily dose is the 24-hour total of a specific drug that is taken for regular and breakthrough pain
List 5 common causes of delirium in the palliative population
- Sepsis
- Metabolic or electrolyte disturbances
- Hypoxia
- Organ failure
- Withdrawal from alcohol or medications
- Unmanaged or undermanaged pain
- Sleep deprivation
- Constipation or urinary retention
- Dehydration
- Changes to the patient’s environment or psychosocial situation
What is delirium, what are the three types, and is it a normal part of the dying process?
- abrupt fluctuating disturbances in attention and awareness that represents a change from baseline status
- hypoactive, hyperactive, or mixed
- Not normal! Common, but should be treated to reduce distress of pt + family