Toxicology Quiz Flashcards
What medication causes cardiotoxicity and bone marrow suppression?
Doxorubicin, danorubicin
A patient tries to commit suicide by overdosing on digitalis. What is the most important step in the management of this patient?
Stop digitalis. Anti-dig antibody*** maybe most important. Normalize Mg++ and K+. Atropine (if have bradycardia).
Drugs that induce that induce the P450 system
BCG PQRS Barbiturates Carbamazepine Griseofulvin Phenytoin Quinidine Rifampin St. Johns wart
And chronic alcohol use
Drugs that inhibit the P450 system
PICK EGS Protease inhibitors Isoniazid Cimetidine Ketoconazole Erythromycin Grapefruit juice Sulfonamides
Acute alcohol use
An African American male that goes to Africa develops anemia after taking prophylactic medicine for primary disease prevention. What enzyme is this patient deficient in?
G6PD deficiency and probable medication is primaquine for malaria prophylaxis
A 65 year old male patient taking multiple medications presents with gynecomastia. Which of the following meds is most responsible for this patients gynecomastia? Digitalis, cimetidine, or spironolactone?
Some Drugs create awkward knockers
Spironolactone, Digitalis, Cimetidine, Alcohol (chronic use), Ketoconazole
Think of Spironolactone and Ketoconazole as the main ones and the most potent ones.
A patient presents with tinnitus, dizziness, headaches, and GI distress, What drug is causing these symptoms?
This is cinchonsim. Quinidine or quinine.
What medications are known for causing drug induced lupus?
SHIPP w/ anit-histone antibody Sulfonamides Hydralazine Isoniazid Phenytoin Procainamide
