Toxicology Part II Flashcards

1
Q
  1. Signs and symptoms
    A. Dizziness, coughing, sneezing, tinnitus, hallucinations/delusions, ataxia, confusion, aggression, seizures
  2. Management
    A. DO NOT agitate, remove from offensive environment, initiate aggressive oxygen (15 L/min NRB; intubate if indicated), initiate IV access, transport
  3. Aliphatic hydrocarbons - CAUTION: airway irritators, CNS depressants, AVOID catecholamines (epi and dopamine), consider beta blockers
A

Volatile solvents

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2
Q
  1. Signs and symptoms
    A. Confusion, dizziness, nausea/vomiting, open sores around mouth and/or nose, ataxia, irritable, aggressive
  2. Management
    A. DO NOT agitate, remove from offensive environment, initiate aggressive oxygen (15 L/min NRB; intubate if indicated), initiate IV access, transport
A

Aerosols

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3
Q
  1. Signs and symptoms
    A. Flushed face, cool skin, hypotension, tachycardia, nausea/vomiting, dizziness, relaxation of vessel tone, slowed perception of time
  2. Management
    A. Oxygen - 15 L/min NRB, IV access, transport
A

Anesthetics

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4
Q
  1. Effects
    A. Increased heart rate, vomiting, agitation, confusion, hallucinations, anxiety, paranoia, increased blood pressure
  2. Withdrawal symptoms
    A. Headache, anxiety, depression, irritability
  3. Management - supportive, manage airway
A

K2

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5
Q
  1. Effects
    A. Risk of HIV, hepatitis/other infectious diseases from shared needles, death
  2. Signs and symptoms
    A. Increased heart rate and blood pressure, euphoria, increased sociability and sex drive, paranoia, agitation, hallucinations, violent behavior, sweating, nausea/vomiting, insomnia, irritability, dizziness, depression, panic attacks, reduced motor control, cloudy thinking
  3. Management - supportive
A

Bath salts

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6
Q
  1. Effects - in rare cases associated with heavy use
    A. Psychotic reactions: fear, anxiety, grandiose delusions (fantastical beliefs of superior qualities such as fame, power, wealth), hallucinations, paranoia
  2. Signs and symptoms
    A. Euphoria, increased alertness and arousal, HTN, tachycardia, depression, paranoia, headaches, loss of appetite, insomnia, fine tremors, loss of short-term memory, gastrointestinal disorders, increased risk of MI
  3. Management - supportive
A

Khat

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7
Q

What is the alcohol CAGE questionnaire?

A

Cut down - have you ever felt the need to cut down on your drinking?
Annoyed - have you ever felt annoyed by criticism of your drinking?
Guilty - have you ever had guilty feelings about drinking?
Eye opener - have you ever taken a drink first thing in the morning as an eye opener?

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8
Q

What are the physical presentations of alcohol abuse?

A
  1. Atrophy of temporal and shoulder muscle and testes
  2. “Spider” and “paper-money” skin
  3. Sparse body hair, gynomastia
  4. Enlarged liver and spleen
  5. Distended abdomen (ascites) and abdominal veins
  6. Increased xiphoid-umbilical distance
  7. Edema to ankles, jaundice, and palmar erythema
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9
Q

What is the treatment for alcohol abuse?

A
  1. Establish and maintain the airway
  2. Determine if other drugs are involved
  3. Establish IV access - lactated ringer’s or normal saline
  4. Consider medications - thiamine and D10W
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10
Q
  1. Signs and symptoms
    A. Coarse tremor of hands, tongue, eyelids; nausea, vomiting, general weakness, anxiety; tachycardia, sweating, HTN, hallucinations, irritability, or depressed mood, poor sleep; increased sympathetic tone, orthostatic hypotension
A

Withdrawal syndrome (delirium tremens)

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11
Q
  1. Used to discourage drinking in alcoholics
  2. Creates blurred vision, chest pain, confusion, dizziness or fainting, fast or pounding heartbeat, flushing or redness of face, increased sweating, nausea and vomiting, troubled breathing, weakness
  3. Symptoms last as long as alcohol is in system (30 min to several hours)
  4. On rare occasions, severe reactions cause heart attack, unconsciousness, convulsions, death
  5. Treatment is supportive - maintain ventilation, treat seizures
A

Antibuse reaction

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