Toxicology Flashcards
1
Q
Methods to measure TDM
A
Immunoassay
TLC
MS
GSMC
2
Q
Acute poisoning substances
A
Cyanide
Carbon monoxide
Salicylates
acetaminophen
3
Q
Carbon monoxide
A
affinity for hgb is 200 times more than o2
4
Q
Lead
A
blocks heme pathway
5
Q
TDM
A
must wait until steady state is reached
takes 5.5 half lives to reach steady state
peaks 1 -2 after oral dose
6
Q
common TDM antibiotics
A
Gentamicin (Aminoglycosides)
Vancomycin (Glycoprotein)
7
Q
Gentamicin (Aminoglycosides)
A
inhibit bacterial protein synthesis, treatment for gram neg
8
Q
Vancomycin (Glycoprotein)
A
inhibit cell wall synthesis, treatment for gram pos
9
Q
Cardioactive drugs
A
Digoxin Quinidine Procainamide Disopyramide Lidocaine
10
Q
Anticonvulsants
A
treatment for seizures Phenytoin Phenobarbital Valproic Acid Primidone
11
Q
What anticonvulsants is highly protein bound
A
phenytoin
12
Q
Psychotropics
A
antidepressants
Tricyclics
Lithium
13
Q
Lithium
A
used for bipolar disorder
14
Q
Bronchodilators
A
Thepohylline
Caffeine
