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CVS 1 > Toxicology > Flashcards

Toxicology Flashcards

1
Q

what are signs of ibuprofen intoxication?

A

vomiting and GI haemorrhage

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2
Q

what is the toxic dose of ibuprofen for renal system?

A

175mg

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3
Q

what is the difference between 1st and 2nd gen coumarins

A

2nd gen are more potent with longer half life

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4
Q

how would you diagnose coumarin poisoning

A

prolonged cpagulation time - PT and APTT

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5
Q

what substance in chocolate is toxic to dogs?

A

methylxanthines - theobromine

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6
Q

what are signs of chocolate poisoning in dogs

A

CNS stimulation and respiratory affects - tachycardia, arrhythmia, seizures, vomiting and abdominal pain

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7
Q

why are cats susceptable to paracetamol poisoning

A

lack the glucoronidation pathway with detoxifies it in the liver

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8
Q

what would you see in the blood of a cat with paracetamol poisoning

A

heinz bodies

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9
Q

what are the clinical sigsn of paracetamol poisoning in cats

A

methaemaglobinaemia dysponea, cyanosis , hypothermia and brown mucous membranes

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10
Q

what are the signs of paracetamol poisoning in dogs

A

hepatic failure - oxidative stress to hepatocytes

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11
Q

what is permethrin found in

A

flea treatments

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12
Q

signs of permethrin poisoning in cats

A

hypersalivation, vomiting, ataxia and seizures

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13
Q

what are metaldyhydes

A

slug pellets

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14
Q

signs of metaldehyde poisoning

A

anxiety, hyperaesthesia, salivation, tremors, ataxia and tachycardia

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15
Q

what body system do lillies affect in cats

A

nephrotoxicity - renal failure

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16
Q

what is benzalkonium chloride found in and what are clinical signs of poisoning

A

household cleaners

tongue ulceration, skin irritation and salivation

17
Q

what is ethylene glycol and what is used as an antidote?

A

antifreeze and screen washer - use alcohol

18
Q

where is salbutamol found and what would you treat it with

A

asthma inhalers - b blockers ( inhalers contain b agonists)

CVS 1 (20 decks)

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