Toxicology

Question 1

Branch of pharmacology that encompasses the deletrious effects of chemicals on biologic systems

Answer 1

Toxicology

Question 2

Area of toxicology that deals with the effects of agents found in the environment

Answer 2

Environmental Toxicology

Question 3

Area of toxicology that deals with the toxic effects of chemicals found in the workplace

Answer 3

Occupational Toxicology

Question 4

What is the most common air pollutant?

Answer 4

Carbon Monoxide (50%)
Sulfur Oxides (18%)

Question 5

What is the treatment for Carbon Monoxide Poisoning?

Answer 5

Removal of the souce of CO and 100% oxygen in a Hyperbaric chamber

Question 6

Treatment for organophosphate poisoning.

Answer 6

Atropine + Pralidoxime

Question 7

This is a bipyridyl herbicide used extensively to kill weeds on farms and for highway maintenance

Answer 7

Paraquat

Question 8

What is the most common effect of Polychlrinated Biphenyls?

Answer 8

Dermatototoxicty (Acne, erythema, folliculitis and hyperkeratosis)

Question 9

Most common signs of toxicity of Dioxins?

Answer 9

Dermatitis and Chloracne (Cystic Acneiform lesions)

Question 10

What cancer is caused by Asbestos?

Answer 10

Mesothelioma

Question 11

What is the treatment for Chronic Inorganic Lead Poisoning (Plumbism)?

Answer 11

EDTA +- Dimercaprol

Oral Succimer for outpatients

Question 12

What is the characteristic sign of Chronic Inorganic Lead Poisoning?

Answer 12

Wrist-drop (Peripheral Neuropathy)

Question 13

What is the treatment for Organic Lead Poisoning?

Answer 13

Succimer

Question 14

These are characteristic transverse bands in the nails of patients with Chronic Arsenic Poisoning

Answer 14

Mee’s Lines

Question 15

Whhat is the characteristic change in the skin of patients with Chronic Arsenic Poisoning?

Answer 15

Mil and Roses Complexion (raindrop hyperpigmentation)

Question 16

What is the treatment for Chronic Arsenic Poisoning?

Answer 16

Dimercaprol

Question 17

What is the treatment for Acute Inorganic Mercury Poisoning?

Answer 17

Oral succimer or IM Dimercaprol

Question 18

What is the treatment for Chronic Inorganic Mercury Poisoning?

Answer 18

Succimer and Unithiol

Question 19

Why is dimercaprol not used in Chronic Inroganic Mercury Poisoning?

Answer 19

Because it may redistribute mercury to the CNS

Question 20

What is the classic presentation of Organic Mercury Poisoning?

Answer 20

Miramata Disease (Cerbral Palsy, Deafness, Blindness and Mental Retardation)

Question 21

What is the treatment for Iron Poisoning?

Answer 21

Deferoxamine

Question 22

What is the treatment for copper poisoning and Wilson’s Disease?

Answer 22

Penicillamine

Question 23

Used in acute severe arsenic poisining and acute severe mercury poisoning and lead poisoning

Answer 23

Unithiol

Question 24

What are the drugs that cause Drug-Induced Lupus?

Answer 24

It's HIPP to have lupus.
H - Hydralazine
I - Isoniazid
P - Procainamide
P - Penicillamine

Question 25

What is the treatment for Sedative-Hypnotic Poisoning?

Answer 25

For Benzodiazipine Overdose -> Flumazenil | For Barbiturate Overdoses -> Supportive

Question 26

What are the signs and symptoms of Aspirin poisoning?

Answer 26

``` CHAFS C - Coma H - Hyperventilation A - Acidosis (HAGMA) F - Fever S - Seizure ```

Question 27

What are the signs and symptoms of Antimuscarinic Poisoning?

Answer 27

``` HOT as a hare (hyperthermia) DRY as a bone RED as a beet BLIND as a bat (Mydriasis) MAD as a hatter (delirium and hallucinations) ```

Question 28

What is the treatment for Opioid Overdose?

Answer 28

Naloxone

Question 29

What are the signs and symptoms of Opioid overdose?

Answer 29

PCR P - Pupillary Constriction C - Comatose state R - Respiratory Depression

Question 30

What are the signs and symptoms of TCA overdose?

Answer 30

3 C's Coma Convulsions Cardiotoxicity

Question 31

What is the treatment ffor TCA overdose?

Answer 31

Sodium Bicarbonate

Question 32

What is the antidote for Acetaminophen?

Answer 32

Acetylceysteine

Question 33

What is the antidote for Cholinesterase Inhibitors?

Answer 33

Atropine

Question 34

Antidote for quinidine and TCA's?

Answer 34

Bicarbonate

Question 35

What is the antidote for Fluoride and CCBs?

Answer 35

Calcium

Question 36

What is the antidote for Digoxin Toxicity?

Answer 36

Digibind

Question 37

What is the antidote for Caffeine, Theophylline and sympathomimetic toxicity?

Answer 37

Esmolol

Question 38

What is the antidote for methanol and ethylene glyccol poisoning?

Answer 38

Fomepizole

Question 39

What is the antidote for Beta blockers?

Answer 39

Glucagon

Question 40

What is the antidote for heparin?

Answer 40

Protamine Sulfate

Question 41

What is the antidote for Warfarin?

Answer 41

Vitamin K / FFP