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semester 3 patho > toxicology > Flashcards

toxicology Flashcards

1
Q

Ingestion(taste)

A

Strong acids and alkalines
Hydrocarbons/petroleum based distillates, methanol, ethylene glycol, isopropanol
Mercury
Cyanide
Organophosphates
Toxic plants
Food poisoning
Botulinum
Drugs ingested
Acetaminophen
Salicylates

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2
Q

Inhalation(smell)

A

Hydrocarbons
Soluble gases – ammonia, chlorine, polyvinyl chloride
Low solubility/insoluble chemically produced gases – nitrogen dioxide
sulfides*
Hydrogen cyanidePh.96
Metal fumes – arsenic, mercury
Carbon monoxide* Pg.90
Drugs smoked
Chemotherapeutic drugs

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3
Q

surface contact(touch)

A

Organophophates(human-made chemicals that poison insects and mammals.)
Carbamates( sprays or baits to kill insects )
Chemotherapeutic agents(
Transdermal patches (nitro, fentanyl etc.)

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4
Q

Injection(through blood)

A

Venom of reptiles/snakes
Ticks and spiders as vectors or those insects secreting venom or toxins
Drugs administered through IV

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5
Q

Opioids / Narcotics

A

hydrocodone (Vicodin)
oxycodone (Oxycontin, Percocet)
oxymorphone (Opana)
morphine (Kadian, Avinza)
Codeine
Fentanyl
hydromorphone (Dilaudid)
Merperidine
Tapentadol
Tramadol
Methadone
Bupenorphine
Heroine

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6
Q

Cholinergic/anti-cholinesterase

A

Organic phosphorus compounds
Carbamates
Arecholine
Pilocarpine
Urecholine (Betanechol)
Carbachol
Choline
Metacholine
Physostigmine
Sarin
Some mushrooms

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7
Q

Anticholinergic

A

Atropine (huge dose)
Scopolamine
Glycopyrrolate benztropine
Tryhexyphenidyl
Tricyclic antidepressants
Amitriptyline
Amosapine
Doxepin
Imipramine
Protriptyline
Trimipramine
Clomipramine

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8
Q

Adrenergic / Sympathomimetic

A

EPI
Cocaine
Amphetamines(meth)
Pseudoephedrine(decongestants)
Ventolin

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9
Q

Sedative / Hypnotic

A

Benzodiazepines
Barbiturates
Alcohols
GHB
(Diazepam, Lorazepam, Phenobarital, Clonazepam)

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10
Q

Serotonin Syndrome

A

MAOIs
- selegiline
- isocarboxazid
- phenelzine
- tranylcypromine

SSRIs
- Fluoxetine
- Paroxetine
- Sertaline
- citalopram

Amlodipine
Dextromethorphan

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11
Q

Hallucinogen

A

PCP
LSD
Mescaline
Psilocybin
DMT

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12
Q

GABA

A

INTOXICATION
- Increased::: Dis inhibition, sedation, loss of balance

WITHDRAWAL
- Decreased::: Anxiety, Insomnia, Seizures

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13
Q

EPINEPHRINE

A

INTOXICATION
- increased:::Hypertension

WITHDRAWAL
- increased:::hypertension,Tachycardia

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14
Q

L-GLUTAMIC ACID

A

INTOXICATION
- decreased:::memory disruption
WITHDRAWAL
- increased::: delirium, seizures

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15
Q

SEROTONIN

A

INTOXICATION
-increased::: sedation, euphoria
WITHDRAWAL
- decreased::: insomnia, mood disorders

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16
Q

DOPAMINE

A

INTOXICATION
-increased::: mood elevationm
WITHHDRAWAL
- Decreased:: dysphoria(dissatisfaction)

semester 3 patho (9 decks)

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