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NAVLE Prep > Toxicology > Flashcards

Toxicology Flashcards

1
Q

How does black widow cause paralysis?

A

Acetylcholine binds Ca channels

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2
Q

How does warfarin tox work?

A

Anticoagulant (2,7,9,10)
Prolongs PT

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3
Q

What is brodifacoum?

A

Vitamin K antagonist

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4
Q

Cholecalciferol toxicity

A

Fatal hypercalcemia
Increased phosphorus

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5
Q

Bromethalin toxicity

A

CNS

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6
Q

Treatment for ethylene glycol

A

4-MP or ethanol

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7
Q

Organophosphate toxicity

A

Inhibits acetylcholinesterase
Hypersalivate, bloat

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8
Q

Treatment for organophosphate tox

A

Atropine or 2-PAM

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9
Q

Strychnine MA

A

Glycine antagonist
Get tremors

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10
Q

Strychnine treatment

A

Methocarbomol

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11
Q

Lillies that accumulate calcium oxalate

A

Peace and cala

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12
Q

What does red maple leaf tox in horses cause

A

Heinz body anemia

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13
Q

Slaframine (moldy red clover)

A

Slobbers

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14
Q

Cantharadin in horses

A

Colic
Cardio shock
Hematuria

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15
Q

Ergot tox in horses

A

Alkaloids
Thrombosis
Colic

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16
Q

Yellow star thistle toxicity

A

Nigropalladial myelomalacia
Loss of prehension
Grave prognosis

17
Q

Locoweed (swainsonine) toxicity

A

Behavior change
Abortion

18
Q

Fescue tox in horses

A

Ergopeptine alkaloids—dopamine agonist
Repro failure in nares
Prolactin suppression
Hoof sloughing

19
Q

Bracken fern toxicity

A

Marrow suppression
Enzootic hematuria
Polioencephalomalacia in horses

20
Q

Milkweed, gossypol, oleander, etc toxicity

A

Acute death
Arrhythmias

21
Q

Ionophore tox in horses

A

Myocardial necrosis
DCM
Hemoglobinuria

22
Q

Perilla mint toxicity

A

Dyspnea
Frothing at mouth

23
Q

Causative agents of fog fever

A

Brassica plants
Tryptophan to 3-MI
Lush forage

24
Q

Moldy sweet potatoes (fusarium)

A

4-IP
Grunt, cough, distress

25
Q

Examples of pyrrolizidine alkaloids

A

Fiddleneck
Groundsel
Ragwort
Senecio
Larkspur

26
Q

Pyrrolizidine alkaloid effects (liver)

A

Inhibit hepatocyte mitosis
Megalocytosis, peripheral fibrosis, bile duct hyperplasia

27
Q

Pyrrolizidine alkaloid effects (other)

A

Secondary photosensitization
Primary photosensitization—St Johns Wort, Brassica, Hypericum

NAVLE Prep (8 decks)

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