Clin Path Flashcards

1
Q

What is anisocytosis?

A

Different sized cells

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2
Q

What do nRBCs indicate?

A

Heat stroke, trauma, marrow injury, regeneration

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3
Q

What do poikilocytes indicate?

A

Liver disease, chemo

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4
Q

What do acanthocytes indicate?

A

Liver issue with cholesterol/phospholipid ratio, HSA, vasculitis

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5
Q

What does agglutination indicate?

A

IMHA

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6
Q

What do codocytes indicate?

A

Increased erythropoeisis

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7
Q

What do eccentrocytes and Heinz bodies indicate?

A

Oxidative injury

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8
Q

What do echinocytes indicate?

A

Snake bite

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9
Q

What does hypochromasia indicate?

A

Regeneration, iron deficiency

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10
Q

What does polychromatic indicate?

A

Regeneration

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11
Q

What/why does rouleaux occur?

A

Fibrinogen and globulins, electrostatic forces

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12
Q

What do schistocytes and/or keratocytes indicate?

A

DIC, vasculitis, some sort of fragmentation process

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13
Q

What do spherocytes indicate?

A

IMHA

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14
Q

What are aggregate reticulocytes?

A

Nuclear material condensed
Immature, regeneration

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15
Q

What can Howell-Jolly bodies indicate?

A

Can be normal in cats
Regeneration
Steroids

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16
Q

Corticosteroid response leukogram

A

Demarginates the marginal pool
Mature neutrophilia with lymphopenia

17
Q

Epinephrine leukogram

A

Increased PCV
Mature neutrophilia with lymphocytosis
Increased glucose

18
Q

Toxic neutrophil changes

A

Dohle bodies, darker cytoplasm, foamy cytoplasm

19
Q

Leukemoid response

A

Many segmented neutros, few bands, 1-2 monos

20
Q

Increased MCV

A

Macrocytic
Agglutination, FeLV in cats with no other abnormalities

21
Q

Decreased MCHC

A

Hypochromic
Iron deficiency anemia, chronic blood loss

22
Q

What does a macrocytic hypochromic anemia indicate?

A

Increased erythropoiesis

23
Q

Relative erythrocytosis

A

Not true
Due to plasma change
Hemoconcentration, splenic contraction

24
Q

Absolute erythrocytosis

A

Secondary—increased erythropoietin, appropriate (hypoxia), vs inappropriate (neoplasia, renal disease)

25
Q

What does eosinophilic inflammation indicate?

A

Hypersensitivity
Mast cell
Parasitic
Fungal

26
Q

What does granulomatous/pyogranulomatous inflammation indicate?

A

Foreign body
Higher bacteria
Fungi

27
Q

What does macrophagic inflammation indicate?

A

Mycobacterium

28
Q

What does suppuration inflammation indicate?

A

Degenerate—infectious, gram negative bacteria
Non-degenerate—immune, neoplasia, sterile process

29
Q

If macrophages are consuming RBCs, what is occurring and since when?

A

Hemorrhage, and recently (less than a few hours)