Toxicological Test and Endpoints of Toxicity

Question 1

Which area of Vet med focuses on assessing the safety of animal-derived foods & the likelihood of undesireable exposure of humans?

Answer 1

Vet Public Health

Question 2

Which branch of toxicology deals w/ exposure of humans & animals to hazardous compounds in the environment & impact of the animal on the environment?

Answer 2

Environmental toxicology

Question 3

Which branch of toxicolgy works w/ animals, their feed, their medication & disease control (pesticides)?

Answer 3

Occupational toxicology

Question 4

________ toxicity determines lethality via single dose toxicity testing.

What value do they look at?

Answer 4

• Experimental toxicity
• LD50 ⇒Lethal to 50% of the population in a single dose

Question 5

What tests do they currently use to determine toxicity b/c LD50 is inhumane?

Answer 5

TD90: how long it takes to see adverse effects such as GI ulceration, kidney damage, etc.

Question 6

_______ toxicology looks at toxic effects that are directly related to exposure.

Answer 6

Clinical toxicology

Question 7

LD50 only shows _____ toxicity?

Answer 7

Acute toxicity