Toxicity-antineoplastic immunosup

Question 1

Agent associated with small cortical hemorrhagic infarcts due to superior sagittal sinus thrombosis

Answer 1

L-asparaginase

Question 2

Agent associate with a multifocal necrotizing leukoencephalopathy

Answer 2

BCNU

Question 3

Agent associated with posterior reversible encephalopathy syndrome (PRES)

Answer 3

Calcineurin inhibitors

Question 4

Class of agents associated with white matter necrosis

Answer 4

Alkylating agents

Question 5

Agent associated with white matter necrosis and vascular abnormalities most severe in the lentiform nuclei

Answer 5

Methotrexate

Question 6

Class of agents associated with an inflammatory cerebral demyelinating disease and a necrotizing leukoencephalopathy most severe in the occipital lobes

Answer 6

Nucleoside analogs

Question 7

Agent associated with a periventricular perivascular mononuclear infiltrate

Answer 7

Metrizamide

Question 8

Agent associate with atrophy of the cerebellar vermis and hemispheres

Answer 8

Phenytoin