toxicity

Question 1

management of lithium toxicity

Answer 1

initial= IV isotonic saline (sodium chloride)

severe = haemodyalisis

Question 2

management cocaine toxicity

Answer 2

chest pain= GTN + benzodiazepine

hypertension= sodium nitroprusside + benzodiazepine

Question 3

myadrisis
hypertonia/ hyperreflexia
wide QRS
agitation + psychosis/ hallucination
may be brady or tachycardia

what mat be causing toxicity

Answer 3

cocaine

Question 4

criteria for liver transplant after paracetamol overdose

Answer 4

Arterial pH < 7.3, 24 hours after ingestion

or all of the following:
prothrombin time > 100 seconds
creatinine > 300 µmol/l
grade III or IV encephalopathy

Question 5

someone has had a paracetamol overdose and is receiving an IV infusion acetylcysteine

-they begin to vomit + develop urticaria

Answer 5

Anaphylactoid reactions to IV acetylcysteine are generally treated by

-stopping the infusion, then restarting at a slower rate.