Toxicities Flashcards
1
Q
Which drugs increase the risk of Leukemia
A
alkylating agents
2
Q
Which drugs cause hepatotoxicity?
A
- methotrexate
- 6 MP
- Nitolinib
3
Q
Which drugs cause pulmonary fibrosis?
A
- carmustine and lomustine
- bleomycin
- dasatinib (pulmonary hypertension)
4
Q
Which drugs cause nephrotoxicity?
A
- Cisplatin
- Methotrexate
- carmustine and lomustine
5
Q
Which drugs cause neuropathies?
A
- cisplatin
- oxaliplatin (cold induced)
- taxanes
- vincristine
6
Q
Which drugs cause cardiotoxicity?
A
- anthracyclines
- 5FU
- Vefuramenib and Nilotinib (QT prolongation)
- Trastuzumab (ventricular dysfunction)
- cetuximab
7
Q
Which drugs cause hemorrhagic cysts?
A
cyclophosphamide and ifosphamide
8
Q
Which drug causes thrombocytopenia?
A
carboplatin
9
Q
Which drugs cause flu like symptoms?
A
dacarbazine and temozolomide
10
Q
Which drug causes ototoxicity?
A
cisplatin
11
Q
Which drug causes hand and foot syndrome?
A
5FU
12
Q
Which drugs cause low myelosupression?
A
- cisplatin
- vincristine
- bleomycin
13
Q
which drug causes pancytopenia?
A
dactinomycin
14
Q
which drug causes leukocyte activation syndrome?
A
retinoic acid
15
Q
Which drug causes tumor lysis and PML?
A
rituximab