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neuro final > toxicities > Flashcards

toxicities Flashcards

1
Q

leukoencephalomalacia cause

A

contaminate corn with Fusarium moniliforme

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2
Q

leukoencephalomalacia cause

A

contaminate corn with Fusarium moniliforme

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3
Q

signs of leukoencephalomalacia

A

may resemble viral encephalomyelitidies, hepatic signs, colic

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4
Q

leukoencephalomalacia pathology

A

white matter-liquefactive necrosis, degeneration: cerebral hemisphere, brainstem, cerebellum, spinal cord
cavitation

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5
Q

leukoencephalomalacia tx

A

removal of moldy feed
cathartics
steroids/DMSO

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6
Q

Nigropallidal encephalomalacia cause

A

chronic consumption of yellow star thistle and russian knapweed

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7
Q

Nigropallidal encephalomalacia pathophysiology

A

repin-depletion of glutathione, lactones, inhibition of dopamine release

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8
Q

Nigropallidal encephalomalacia clinical signs

A

acute onset of rigidity of muscles of mastication-inability to prehend or masticate food
mouth hands open and tongue partially protrubes, hypertonicity of facial and masticatory muscles
aimless wandering, circling and ataxia
death from starvation

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9
Q

lead poisoning in horses

A

chronic toxicity
peripheral neuropathies
no acute toxicity

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10
Q

lead poisoning in cattle epidemiology

A

common

major sources-paint, car batteries, oil

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11
Q

lead poisoning in cattle clinical signs

A 
single large ingestion of lead
blindness
ataxia
head pressing
abdominal pain-bloat or diarrhea
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12
Q

lead poisoning in cattle tx

A

rumenotomy
cathrtics
calcium disodium EDTA

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13
Q

salt poisoning

A

high dietary sodium loads
oral electrolyte replacements
CNS signs: blindness, ataxia, seizures
sodium levels over 160 mEq/L

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14
Q

organophosphates

A

product overdose
accidental access to insecticides
inactivate cholinesterases results in over stimulation of PS nerves

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15
Q

clinical signs of organophosphate poisoning

A 
dyspnea
diarrhea
apparent blindness from miosis
protruding tongue
drooling
bloat
collapse
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16
Q

dx of organophosphate poisoning

A

clinical signs

blood cholinesterase activity

17
Q

treatment of organophosphate poisoning

A

atropine

activated charcoal

18
Q

signs of leukoencephalomalacia

A

may resemble viral encephalomyelitidies, hepatic signs, colic

19
Q

leukoencephalomalacia pathology

A

white matter-liquefactive necrosis, degeneration: cerebral hemisphere, brainstem, cerebellum, spinal cord
cavitation

20
Q

leukoencephalomalacia tx

A

removal of moldy feed
cathartics
steroids/DMSO

21
Q

Nigropallidal encephalomalacia cause

A

chronic consumption of yellow star thistle and russian knapweed

22
Q

Nigropallidal encephalomalacia pathophysiology

A

repin-depletion of glutathione, lactones, inhibition of dopamine release

23
Q

Nigropallidal encephalomalacia clinical signs

A

acute onset of rigidity of muscles of mastication-inability to prehend or masticate food
mouth hands open and tongue partially protrubes, hypertonicity of facial and masticatory muscles
aimless wandering, circling and ataxia
death from starvation

24
Q

lead poisoning in horses

A

chronic toxicity
peripheral neuropathies
no acute toxicity

25
Q

lead poisoning in cattle epidemiology

A

common

major sources-paint, car batteries, oil

26
Q

lead poisoning in cattle clinical signs

A 
single large ingestion of lead
blindness
ataxia
head pressing
abdominal pain-bloat or diarrhea
27
Q

lead poisoning in cattle tx

A

rumenotomy
cathrtics
calcium disodium EDTA

28
Q

salt poisoning

A

high dietary sodium loads
oral electrolyte replacements
CNS signs: blindness, ataxia, seizures
sodium levels over 160 mEq/L

29
Q

organophosphates

A

product overdose
accidental access to insecticides
inactivate cholinesterases results in over stimulation of PS nerves

30
Q

clinical signs of organophosphate poisoning

A 
dyspnea
diarrhea
apparent blindness from miosis
protruding tongue
drooling
bloat
collapse
31
Q

dx of organophosphate poisoning

A

clinical signs

blood cholinesterase activity

32
Q

treatment of organophosphate poisoning

A

atropine

activated charcoal

neuro final (8 decks)

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