toxic syndrome Flashcards
Serotonin Syndrome
NMJ: myoclonus, hyperreflexia, tremor
Autonomic: fever, diaphoresis, diarrhea
Altered mental status
Serotonin syndrome tx
Cyproheptadine 5HT2 antagonist
Causes of serotonin syndrome
SSRI
MAOI
TCA
TRAMADOL
TRIPTANS
Causes of NMS
Typical antipsychotics
Atypical
genetic predisposition
symptoms os NMS
fever
myoglobinuria
encephalopathy
muscle rigidity
increase CPK
treatment os NMS
Dantrolene
dopamine agonist
Parkinsonism hyperperxia syndrome symptoms
rigidity
worsen parkinsonism
fever
altered mental status
PHS treatment
dopamine agonist
Levodopa
amantadine
oculogeric crisis symptoms
usually associated with other dystonic movement like blepharospasm, lip smacking, tongue protrusion, laterocollis
oculogeric crisis causes
drug induced: typical and atypcal anthpsychotics
antiemetics
SSRI
Tegretol
oculogeric crisis treatment
Anticholinergic such as benztropine, biperidine dikenrt