toxic epidermal necrolysis Flashcards
1
Q
what
A
lifethreatining skin disoderder most commonly 2ry to drug reaction
skin develops scalded appearance oevr extensive area
2
Q
feaures
A
scalded appearance skin
systemically unwell
positive Nikolsky’s sign
3
Q
Nikolsky’s sigh
A
epidermis seperates with mild lateral pressure
4
Q
drugs known to induce TEN
A
phenytoin sulphonamides allopurinol penicillins carbamezapine NSAIDs
5
Q
Mx
A
stop precipitating factor
supportive care
IVIg
6
Q
potential complication
A
volume loss and electrolyte derrangement