acne vulgaris Flashcards

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1
Q

what

A

common skin disorder usually occuring in adolescence

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2
Q

characterised by

A

obstruction of pilosebaceous follice with keratin plugs which results in comendones, inflamation and pustules

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3
Q

pathophysiology

A
  • follicular epidermal hyperproliferation –> keratin plug which obstructs follicle
  • colonisation by anaerobic bacterria Propionibacterium Acnes
  • inflammation
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4
Q

mild acne

A

open and closed comeodnes

with or without sparse inflammatory lesions

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5
Q

moderate acne

A

widespread non-inflammatory lesions and numerous papules and pustules

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6
Q

severe acne

A

extensive inflammatory lesions

may include nodules, pitting and scarring

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7
Q

1st line Mx

A

single topical therapy

  • topical retinoids
  • benzoyl peroxidase
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8
Q

2nd line Mx

A

topical combination therapy

  • topical antibiotic
  • topical retinoid
  • benzoyl peroxidase
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9
Q

first line oral antib

A

tetracyclines

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10
Q

when should tetracylcines be avoided

A

pregnanct/breastfeeding women

kids < 12yrs

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11
Q

what oral antib can be used in pregnancy for acne

A

erythromycin

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12
Q

Mx - what can be considered as alternative to oral antib in women

A

COCP

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13
Q

what must be prescribes along with oral antib

A

topical retinoid and benzyl peroxidase

reduce risk of antib resistance

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