acne vulgaris

Question 1

what

Answer 1

common skin disorder usually occuring in adolescence

Question 2

characterised by

Answer 2

obstruction of pilosebaceous follice with keratin plugs which results in comendones, inflamation and pustules

Question 3

pathophysiology

Answer 3

• follicular epidermal hyperproliferation –> keratin plug which obstructs follicle
• colonisation by anaerobic bacterria Propionibacterium Acnes
• inflammation

Question 4

mild acne

Answer 4

open and closed comeodnes

with or without sparse inflammatory lesions

Question 5

moderate acne

Answer 5

widespread non-inflammatory lesions and numerous papules and pustules

Question 6

severe acne

Answer 6

extensive inflammatory lesions

may include nodules, pitting and scarring

Question 7

1st line Mx

Answer 7

single topical therapy

• topical retinoids
• benzoyl peroxidase

Question 8

2nd line Mx

Answer 8

topical combination therapy

• topical antibiotic
• topical retinoid
• benzoyl peroxidase

Question 9

first line oral antib

Answer 9

tetracyclines

Question 10

when should tetracylcines be avoided

Answer 10

pregnanct/breastfeeding women

kids < 12yrs

Question 11

what oral antib can be used in pregnancy for acne

Answer 11

erythromycin

Question 12

Mx - what can be considered as alternative to oral antib in women

Answer 12

COCP

Question 13

what must be prescribes along with oral antib

Answer 13

topical retinoid and benzyl peroxidase

reduce risk of antib resistance