Tox. Osweiller. Toxicants Affects The ANS Flashcards

1
Q

Amanita muscaria, A pantherina

MOA
CHARACTERISTICS

A

Contain ibotenic acid and muscimol, which compete with the inhibitory neurotransmitter GABA

Seizures, opisthotonos, anticholinergic signs similar to those seen with atropine

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2
Q

Atropine or atropine-like plants ( Datura, Hyoscyamus, Jessemine, physalis)

MOA
Characteristics

A

Competitive antagonism of acetylcholine receptors at parasympathetic postganglionic nerve terminals

Tachycardia, GI atony, mydriasis, hypo-salivation, disturbed vision, hallucinations

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3
Q

Glycopyrrolate

MOA
Characteristics

A

Drug similar action to that of atropine, but does not cross the BBB, therefore no CNS effects

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4
Q

Scopalamine

MOA
Characteristics

A

Competitive antagonism of acetylcholine receptors at parasympathetic postganglionic nerve terminals

Tachycardia, GI atony, mydraisis, hyposalivation, disturbed vision, hallucinations

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